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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GPR56 Polyclonal Antibody

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货号 TMAB-06725

Anti-GPR56 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GPR56。Anti-GPR56 Polyclonal Antibody 可用于 WB。

Anti-GPR56 Polyclonal Antibody

Anti-GPR56 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06725

Anti-GPR56 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GPR56。Anti-GPR56 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-GPR56 Polyclonal Antibody is a Rabbit antibody targeting GPR56. Anti-GPR56 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Pig,Cow,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane. Multi-pass membrane protein.
组织特异性Widely distributed with highest levels found in thyroid gland, brain and heart. Expressed in a great number of tumor cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景G protein-coupled receptors (GPRs or GPCRs), also known as seven transmembrane receptors, heptahelical receptors, or 7TM receptors, are members of the largest protein family and play a role in many different stimulus-response pathways. G-protein coupled receptors mediate extracellular signals into intracellular signals (G-protein activation). They respond to a great variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR proteins are integral seven-pass membrane proteins with some conserved amino acid regions. G-protein coupled receptor 56 (GPR56), also designated TM7XN1 protein, contains one GPS domain. GPR56 plays an important role in cell-cell interactions and is widely expressed, with highest levels detected in brain, heart and thyroid gland. Defects in the gene encoding for GPR56 can cause bilateral frontoparietal polymicrogyria (BFPP) which is characterized by disorganized cortical lamination.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GPR56
抗原种属
Human
基因名称
ADGRG1
基因ID
9289
蛋白名称
Adhesion G-protein coupled receptor G1
Uniprot ID
Q9Y653
功能
GPR56 contains 7 transmembrane domains as well as a mucin-like domain and cysteine box in the N-terminal region. Its expression is widely distributed and the highest levels can be found in brain, thyroid gland and heart. It is also expressed in a great number of tumor cells. Results show that mutations in GPR56 cause a human brain cortical malformation called bilateral frontoparietal polymicrogyria (BFPP); data suggest that GPR56 signaling plays an essential role in regional development of human cerebral cortex.
化学信息
分子量Theoretical: 78 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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