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IL-5 Protein, Human, Recombinant

产品编号 TMPY-03915

别名: TRF, 白介素, EDF, interleukin 5, IL-5, 白细胞介素

IL-5 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.1 kDa and the accession number is P05113.

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IL-5 Protein, Human, Recombinant

规格	价格/CNY		货期	数量
5 μg	￥ 560		现货
10 μg	￥ 910		5日内发货
20 μg	￥ 1,470		5日内发货
50 μg	￥ 2,750		5日内发货
100 μg	￥ 4,430		5日内发货

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参考文献

生物活性	Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.1-0.5 ng/mL.
产品描述	IL-5 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.1 kDa and the accession number is P05113.

种属	Human
表达系统	E. coli
标签	Tag Free
蛋白编号	P05113
别名	TRF, 白介素, EDF, interleukin 5, IL-5, 白细胞介素
蛋白构建	Human IL5 (P05113) (Ile20-Ser134)
蛋白纯度	> 95 % as determined by SDS-PAGE
分子量	13.1 kDa (predicted)

内毒素	Please contact us for more information.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes) and has been found in a wide variety of body cells. Interleukin 5 or IL-5 is produced by T helper-2 cells and mast cells. It helps to stimulate B cell growth and increase immunoglobulin secretion and is considered a key mediator in eosinophil activation. Interleukin 5 (IL-5) has long been associated with several allergic diseases, including allergic rhinitis and asthma. Growth in the number of circulating, airway tissue, and induced sputum eosinophils have been observed in patients with these diseases. IL-5 also had something with the terminally differentiated granulocyte eosinophils. IL-5 was originally found as an eosinophil colony-stimulating factor. It has been proved to be a major regulator of eosinophil accumulation in tissues and can modulate eosinophil behavior at every stage from maturation to survival.

参考文献

1. Milburn MV,et al.(1993) A novel dimer configuration revealed by the crystal structure at 2.4 A resolution of human interleukin-5. Nature. 363(6425): 172-176. 2. Lee JS,et al.(1989) The IL-4 and IL-5 genes are closely linked and are part of a cytokine gene cluster on mouse chromosome 11. Somat Cell Mol Genet. 15(2): 143-152. 3. Woodcock JM,et al.(1994) Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF. EMBO J. 13 (21): 5176-85.

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Keywords

IL-5 Protein, Human, Recombinant TRF IL 5 白介素 IL5 EDF interleukin 5 IL-5 白细胞介素 recombinant recombinant-proteins proteins protein

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