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顶部生物活性储存和溶解信息计算器

Anti-FGFR1 Antibody (6L433)

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Anti-FGFR1 Antibody (6L433)
产品编号 TMAY-03163
别名 OGD, N-SAM, KAL2, HRTFDS, HH2, HBGFR, FLT-2, FLT2, FLG, fibroblast growth factor receptor 1, FGFR1 α (IIIc), FGFR-1, FGFBR, CEK, CD331, bFGF-R-1, BFGFR

Anti-FGFR1 Antibody (6L433) 是一种 Rabbit 抗体，靶向 FGFR1。Anti-FGFR1 Antibody (6L433) 可用于 ELISA。

Anti-FGFR1 Antibody (6L433)

Anti-FGFR1 Antibody (6L433)

Rating icon 还可以
Anti-FGFR1 Antibody (6L433)
产品编号 TMAY-03163 别名 OGD, N-SAM, KAL2, HRTFDS, HH2, HBGFR, FLT-2, FLT2, FLG, fibroblast growth factor receptor 1, FGFR1 α (IIIc), FGFR-1, FGFBR, CEK, CD331, bFGF-R-1, BFGFR

Anti-FGFR1 Antibody (6L433) 是一种 Rabbit 抗体，靶向 FGFR1。Anti-FGFR1 Antibody (6L433) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-FGFR1 Antibody (6L433) is a Rabbit antibody targeting FGFR1. Anti-FGFR1 Antibody (6L433) can be used in ELISA.
别名OGD, N-SAM, KAL2, HRTFDS, HH2, HBGFR, FLT-2, FLT2, FLG, fibroblast growth factor receptor 1, FGFR1 α (IIIc), FGFR-1, FGFBR, CEK, CD331, bFGF-R-1, BFGFR
Ig Type
Rabbit IgG
克隆号
6L433
交叉反应
Mouse
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse FGFR1 / CD331 (rM FGFR1 / CD331; TMPY-01781; P16092-1; Met 1-Glu 376).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. Fibroblast growth factors (FGFs) (FGF1 - 10 and 16 - 23) are mitogenic signaling molecules that have roles in angiogenesis, wound healing, cell migration, neural outgrowth and embryonic development. FGFs bind heparan sulfate glycosaminoglycans, which facilitates dimerization (activation) of FGF receptors. FGFR1 is a full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of FGFR1 interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. CD331 can be detected in astrocytoma, neuroblastoma and adrenal cortex cell lines. Some isoforms are detected in foreskin fibroblast cell lines, however isoform 17, isoform 18 and isoform 19 are not detected in these cells. Defects in FGFR1 are a cause of Pfeiffer syndrome ，idiopathic hypogonadotropic hypogonadism， Kallmann syndrome type 2, osteoglophonic dysplasia and trigonocephaly non-syndromic.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse FGFR1 / CD331 protein (TMPY-01781)
抗原种属
Mouse
研究领域
Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

关键词

KAL-2KAL 2HH-2HH 2FLT 2FGFR1FGFR 1CD-331CD 331

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