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Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. HSD11B2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 46.1 kDa and the accession number is P80365.
别名 Short chain dehydrogenase/reductase family 9C member 3, SDR9C3, NAD-dependent 11-beta-hydroxysteroid dehydrogenase, HSD11K, HSD11B2, Corticosteroid 11-beta-dehydrogenase isozyme 2, 11-DH2, 11-beta-hydroxysteroid dehydrogenase type II (11-HSD type II;11-beta-HSD type II), 11-beta-hydroxysteroid dehydrogenase type 2, 11-beta-HSD2
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. HSD11B2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 46.1 kDa and the accession number is P80365.

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 539 | 3日内发货 | |
| 10 μg | ¥ 885 | 3日内发货 | |
| 20 μg | ¥ 1,470 | 3日内发货 | |
| 50 μg | ¥ 2,190 | 3日内发货 | |
| 100 μg | ¥ 2,970 | 现货 | |
| 200 μg | ¥ 4,650 | 20日内发货 | |
| 500 μg | ¥ 8,470 | 20日内发货 |
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| 产品描述 | Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. HSD11B2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 46.1 kDa and the accession number is P80365. |
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| 研究背景 | Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. |
| 种属 | Human |
| 表达系统 | P. pastoris (Yeast) |
| 标签 | N-6xHis |
| 蛋白编号 | P80365 |
| 氨基酸序列 | MERWPWPSGGAWLLVAARALLQLLRSDLRLGRPLLAALALLAALDWLCQRLLPPPAALAVLAAAGWIALSRLARPQRLPVATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAIELRTCCSPRLRLLQMDLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESVRNVGQWEKRKQLLLANLPQELLQAYGKDYIEHLHGQFLHSLRLAMSDLTPVVDAITDALLAARPRRRYYPGQGLGLMYFIHYYLPEGLRRRFLQAFFISHCLPRALQPGQPGTTPPQDAAQDPNLSPGPSPAVAR |
| 蛋白构建 | 1-405 aa |
| 蛋白纯度 | > 90% as determined by SDS-PAGE. |
| 缓冲液 | Tris-based buffer, 50% glycerol |
| 复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| 别名 | Short chain dehydrogenase/reductase family 9C member 3, SDR9C3, NAD-dependent 11-beta-hydroxysteroid dehydrogenase, HSD11K, HSD11B2, Corticosteroid 11-beta-dehydrogenase isozyme 2, 11-DH2, 11-beta-hydroxysteroid dehydrogenase type II (11-HSD type II;11-beta-HSD type II), 11-beta-hydroxysteroid dehydrogenase type 2, 11-beta-HSD2 |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 分子量 | 46.1 kDa (predicted) |
| 运输方式 | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. 实际储存温度请以COA为准 |
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