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Anti-BAFF/TNFSF13B Antibody-PE (9F115)

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Anti-BAFF/TNFSF13B Antibody-PE (9F115)
产品编号 TMAY-00194P
别名 ZTNF4, tumor necrosis factor (ligand) superfamily, member 13b, TNFSF20, THANK, TALL-1, TALL1, DTL, CD257, BLYS, BAFF

Anti-BAFF/TNFSF13B Antibody-PE (9F115) 是一种 PE-conjugated Rabbit 抗体，靶向 BAFF/TNFSF13B。Anti-BAFF/TNFSF13B Antibody-PE (9F115) 可用于 FCM。

Anti-BAFF/TNFSF13B Antibody-PE (9F115)
331

Anti-BAFF/TNFSF13B Antibody-PE (9F115)

Rating icon 还可以
Anti-BAFF/TNFSF13B Antibody-PE (9F115)
产品编号 TMAY-00194P 别名 ZTNF4, tumor necrosis factor (ligand) superfamily, member 13b, TNFSF20, THANK, TALL-1, TALL1, DTL, CD257, BLYS, BAFF

Anti-BAFF/TNFSF13B Antibody-PE (9F115) 是一种 PE-conjugated Rabbit 抗体，靶向 BAFF/TNFSF13B。Anti-BAFF/TNFSF13B Antibody-PE (9F115) 可用于 FCM。

规格价格库存数量
25 T
¥ 890
5日内发货
100 T
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-BAFF/TNFSF13B Antibody-PE (9F115) is a PE-conjugated Rabbit antibody targeting BAFF/TNFSF13B. Anti-BAFF/TNFSF13B Antibody-PE (9F115) can be used in FCM.
别名ZTNF4, tumor necrosis factor (ligand) superfamily, member 13b, TNFSF20, THANK, TALL-1, TALL1, DTL, CD257, BLYS, BAFF
Ig Type
Rabbit IgG
克隆号
9F115
交叉反应
Human
验证活性
Flow cytometric analysis of Human BAFF(CD257) expression on U937 cells. Cells were stained with PE-conjugated anti-Human BAFF(CD257). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用
FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human BLyS / TNFSF13B (rh BLyS / TNFSF13B; TMPY-02775; Q9Y275-1; Ala134-Leu285) and conjugated with PE under optimum conditions, the unreacted PE was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景B lymphocyte stimulator (BLyS), also known as TNFSF13B, CD257 and BAFF, is a single-pass type II membrane protein, which belongs to the tumor necrosis factor family. BAFF is abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. BAFF is a cytokine and serves as a ligand for receptors TNFRSF13B (TACI), TNFRSF17 (BCMA), and TNFRSF13C (BAFFR). These receptors are a prominent factor in B cell differentiation, homeostasis, and selection. BLyS levels affect survival signals and selective apoptosis of autoantibody-producing B cells. Thus, it acts as a potent B cell activator and has been shown to play an important role in the proliferation and differentiation of B cells. Overexpression of BLyS in mice can lead to clinical and serological features of systemic lupus erythematosus (SLE) and Sjögren's syndrome (SS). BLyS is an attractive therapeutic target in human rheumatic diseases. The ability of BLyS to regulate both the size and repertoire of the peripheral B cell compartment raises the possibility that BLyS and antagonists thereof may form the basis of a therapeutic trichotomy. As an agonist, BLyS protein may enhance humoral immunity in congenital or acquired immunodeficiencies such as those resulting from viral infection or cancer therapy.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
PE
其他可选修饰符
Unconjugated
可提供抗体种类
2
抗原信息
免疫原
Recombinant Protein: Human BLyS/TNFSF13B Protein (TMPY-02775)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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关键词

ZTNF-4ZTNF 4TNFSF-20TNFSF 20TALL 1CD-257CD 257

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