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Anti-GDF-15 Antibody (7H179)
还可以产品编号 TMAY-01351
Anti-GDF-15 Antibody (7H179) 是一种 Mouse 抗体，靶向 GDF-15。Anti-GDF-15 Antibody (7H179) 可用于 ELISA(Det)。
Anti-GDF-15 Antibody (7H179)
Anti-GDF-15 Antibody (7H179)
还可以产品编号 TMAY-01351
Anti-GDF-15 Antibody (7H179) 是一种 Mouse 抗体，靶向 GDF-15。Anti-GDF-15 Antibody (7H179) 可用于 ELISA(Det)。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-GDF-15 Antibody (7H179) is a Mouse antibody targeting GDF-15. Anti-GDF-15 Antibody (7H179) can be used in ELISA(Det). |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 7H179 |
| 交叉反应 | Human |
| 应用 | ELISA(Det) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GDF15/MIC-1 (rh GDF15/MIC-1; TMPY-04727; NP_004855.2; Ala197-Ile308). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS with 10% Trehalose, 0.02% Tween 80, pH7.0 |
| 研究背景 | Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not expressed in the normal adult heart but is induced in response to conditions that promote hypertrophy and dilated cardiomyopathy and it is expressed highly in liver. GDF-15 / GDF15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF-15 / GDF15 is synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. GDF-15 / GDF15 overexpression arising from an expanded erythroid compartment contributes to iron overload in thalassemia syndromes by inhibiting hepcidin expression. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | HRP |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human GDF15/MIC-1 Protein (TMPY-04727) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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