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Ephrin A5/EFNA5 Protein, Rhesus, Recombinant (hFc)

产品编号 TMPY-02746

Ephrin A5/EFNA5 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.2 kDa and the accession number is A0A8J8Y8X9.

Ephrin A5/EFNA5 Protein, Rhesus, Recombinant (hFc)

产品编号 TMPY-02746

Ephrin A5/EFNA5 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.2 kDa and the accession number is A0A8J8Y8X9.

规格	价格	库存	数量
100 μg	¥ 2,940	5日内发货

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产品信息

生物活性	Measured by its binding ability in a functional ELISA. Immobilized Rhesus EFNA5-Fc at 10 μg/mL (100 μl/well) can bind biotinylated Rhesus EPHA4 . The EC50 of biotinylated Rhesus EPHA4 is 9.3-21.6 ng/mL.
产品描述	Ephrin A5/EFNA5 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.2 kDa and the accession number is A0A8J8Y8X9.
种属	Rhesus
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	NP_001252657.1
别名	ephrin-A5
蛋白构建	A DNA sequence encoding the rhesus EFNA5 (NP_001252657.1) (Met 1-Asn 203) was fused with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Gln 21
蛋白纯度	> 92 % as determined by SDS-PAGE
分子量	48.2 kDa (predicted)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Ephrin-A5 also known as EFNA5, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. Ephrin-A5/EFNA5 may function actively to stimulate axon fasciculation. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Ephrin-A5/EFNA5 also serves as a cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.