IL12RB1 Protein, Human, Recombinant (hFc)

Synonyms: interleukin-12 receptor β-1 chain, interleukin-12 receptor subunit β-1, interleukin-12 receptor subunit beta-1, interleukin-12 receptor beta-1 chain, IL-12R-β-1, IL-12R-β1, IL-12R-beta-1, IL-12R-BETA1, IL-12RB1, IL12RB1, IL12RB, IL-12R subunit β-1, IL-12R subunit beta-1, IL12R, IL-12 receptor β component, IL-12 receptor subunit β-1, IL-12 receptor subunit beta-1, IL-12 receptor beta component, CD212 antigen, CD212

规格

价格

库存

数量

5 μg

¥ 289

6-8日内发货

10 μg

¥ 460

6-8日内发货

20 μg

¥ 737

5日内发货

50 μg

¥ 1,410

5日内发货

100 μg

¥ 2,670

5日内发货

200 μg

¥ 4,970

5日内发货

500 μg

¥ 12,100

5日内发货

1 mg

¥ 17,300

5日内发货

生物活性

产品描述	Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL12 with only low affinity. IL12 high affinity receptor complex is composed of two subunits designated IL12RB1 and IL12RB2. While IL12RB1 interacts with the IL-12p40 subunit, IL-12p35 is mainly connecting with IL12RB2. This receptor chain is also responsible for transmitting the IL12 signal into the cell. IL12RB1, to the contrary, is also part of the IL23R, where it interacts with the p40 subunit of IL23. IL12RB1 is expressed in activated T cells, NK cells and B cells.
生物活性	Immobilized Human IL-12B, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Human IL-12 R beta 1, hFc Tag with the EC50 of 0.11 μg/ml determined by ELISA.
研究背景	Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL12 with only low affinity. IL12 high affinity receptor complex is composed of two subunits designated IL12RB1 and IL12RB2. While IL12RB1 interacts with the IL-12p40 subunit, IL-12p35 is mainly connecting with IL12RB2. This receptor chain is also responsible for transmitting the IL12 signal into the cell. IL12RB1, to the contrary, is also part of the IL23R, where it interacts with the p40 subunit of IL23. IL12RB1 is expressed in activated T cells, NK cells and B cells.
种属	Human
表达系统	HEK293 Cells
标签	C-hFc (IgG1)
蛋白编号	P42701-1
氨基酸序列	Cys24-Glu540
蛋白构建	Cys24-Glu540
蛋白纯度	> 95% as determined by Bis-Tris PAGE
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	interleukin-12 receptor β-1 chain, interleukin-12 receptor subunit β-1, interleukin-12 receptor subunit beta-1, interleukin-12 receptor beta-1 chain, IL-12R-β-1, IL-12R-β1, IL-12R-beta-1, IL-12R-BETA1, IL-12RB1, IL12RB1, IL12RB, IL-12R subunit β-1, IL-12R subunit beta-1, IL12R, IL-12 receptor β component, IL-12 receptor subunit β-1, IL-12 receptor subunit beta-1, IL-12 receptor beta component, CD212 antigen, CD212
内毒素	< 1 EU/µg as determined by LAL test.

化学信息

分子量	83.85 kDa (predicted); 95-115 kDa (reducing condition, due to glycosylation)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

IL12RB1 Protein, Human, Recombinant (hFc)

IL12RB1 Protein, Human, Recombinant (hFc)

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