IL-12RB1 Protein, Human, Recombinant (hFc)

Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL12 with only low affinity. IL12 high affinity receptor complex is composed of two subunits designated IL12RB1 and IL12RB2. While IL12RB1 interacts with the IL-12p40 subunit, IL-12p35 is mainly connecting with IL12RB2. This receptor chain is also responsible for transmitting the IL12 signal into the cell. IL12RB1, to the contrary, is also part of the IL23R, where it interacts with the p40 subunit of IL23. IL12RB1 is expressed in activated T cells, NK cells and B cells.

规格	价格/CNY		数量
10 μg	￥ 460	5日内发货
50 μg	￥ 1,410	5日内发货
500 μg	￥ 12,100	5日内发货
1 mg	￥ 17,400	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 460

5日内发货

50 μg

￥ 1,410

5日内发货

500 μg

￥ 12,100

5日内发货

1 mg

￥ 17,400

5日内发货

产品描述

种属	Human
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	P42701
别名	IL-12R-β1, IL-12R-BETA1, IL-12 receptor subunit beta-1, IL12RB, IL-12R subunit beta-1, CD212 antigen, IL-12 receptor subunit β-1, interleukin-12 receptor β-1 chain, interleukin-12 receptor beta-1 chain, IL-12 receptor β component, IL12RB1, CD212, interleukin-12 receptor subunit beta-1, interleukin-12 receptor subunit β-1, IL12R, IL-12R subunit β-1, IL-12R-β-1, IL-12RB1, IL-12R-beta-1, IL-12 receptor beta component
氨基酸序列	Cys24-Glu540
蛋白构建	Cys24-Glu540
蛋白纯度	Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
分子量	95-110 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 5% trehalose, 5% mannitol, 0.02% Tween 80, pH8.0.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL12 with only low affinity. IL12 high affinity receptor complex is composed of two subunits designated IL12RB1 and IL12RB2. While IL12RB1 interacts with the IL-12p40 subunit, IL-12p35 is mainly connecting with IL12RB2. This receptor chain is also responsible for transmitting the IL12 signal into the cell. IL12RB1, to the contrary, is also part of the IL23R, where it interacts with the p40 subunit of IL23. IL12RB1 is expressed in activated T cells, NK cells and B cells.

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IL-12RB1 Protein, Human, Recombinant (hFc)

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