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TEM8/ANTXR1 Protein, Human, Recombinant (His)

TEM8/ANTXR1 Protein, Human, Recombinant (His)
产品编号 TMPY-07113

TEM8/ANTXR1 Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q9H6X2-1.

TEM8/ANTXR1 Protein, Human, Recombinant (His)

TEM8/ANTXR1 Protein, Human, Recombinant (His)

TEM8/ANTXR1 Protein, Human, Recombinant (His)
产品编号 TMPY-07113
TEM8/ANTXR1 Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q9H6X2-1.
规格价格库存数量
50 μg
¥ 2,930
期货
大包装 & 定制
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产品信息

生物活性
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述
TEM8/ANTXR1 Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q9H6X2-1.
种属
Human
表达系统
HEK293 Cells
标签C-His
蛋白编号Q9H6X2-1
别名
TEM8,GAPO,FLJ21776,FLJ10601,ATR
蛋白构建
A DNA sequence encoding the Human ANTXR1 (NP_115584.1) (Met1-Ser321) was expressed with a polyhistidine tag at the C-terminus.
蛋白纯度
≥ 95% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC.
分子量33.85 kDa (predicted); 41.1 kDa (reducing contition, due to glycosylation)
内毒素< 1.0 EU per μg protein as determined by the LAL method.
缓冲液Lyophilized from sterile PBS, 10% Glycerol, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
复溶方法
Please refer to the lot-specific COA.
存储
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式In general, Lyophilized powders are shipping with blue ice.
研究背景
ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are serine-threonine protein kinases and belongs to the phosphatidylinositol 3' kinase-like kinase (PIKK) family. Upon recruitment by the DNA damage binding proteins/complexes (ATRIP for ATR; MRN for ATM), ATM/ATR initiate the DNA damage checkpoint by phosphorylating a number of key proteins. ANTXR1 interacts with extracellular matrix proteins and with the actin cytoskeleton. It functions in cell attachment and migration. ANTXR1 also mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It plays a role in the angiogenic response of cultured umbilical vein endothelial cells.

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.