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Anti-ISL1 Antibody (9H190)

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产品编号 TMAH-00639
别名 Islet-1, ISL 1, Insulin gene enhancer protein ISL-1

Anti-ISL1 Antibody (9H190) 是一种抗体,靶向 ISL1。Anti-ISL1 Antibody (9H190) 可用于 ELISA, WB。

Anti-ISL1 Antibody (9H190)

Anti-ISL1 Antibody (9H190)

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产品编号 TMAH-00639 别名 Islet-1, ISL 1, Insulin gene enhancer protein ISL-1

Anti-ISL1 Antibody (9H190) 是一种抗体,靶向 ISL1。Anti-ISL1 Antibody (9H190) 可用于 ELISA, WB。

规格价格库存数量
50 μL
¥ 1,315
5日内发货
100 μL
¥ 2,190
5日内发货
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产品介绍

生物活性
产品描述
Anti-ISL1 Antibody (9H190) is an antibody targeting ISL1. Anti-ISL1 Antibody (9H190) can be used in ELISA, WB.
别名Islet-1, ISL 1, Insulin gene enhancer protein ISL-1
Ig Type
Rabbit IgG
克隆号
9H190
交叉反应
Human
验证活性
Western Blot
-Positive WB detected in: Hela whole cell lysate, SH-SY5Y whole cell lysate, Jurkat whole cell lysate, K562 whole cell lysate
-All lanes: ISL1 antibody at 1:2000
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 40 kDa
-Observed band size: 39 kDa
应用
ELISA, WB
推荐剂量
WB:1:500-1:5000.
抗体种类
Monoclonal
亚细胞定位Nucleus.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Cooperates with the transcription factor POU4F2 to achieve maximal levels of expression of RGC target genes and RGC fate specification in the developing retina. Involved in the specification of motor neurons in cooperation with LHX3 and LDB1. Binds to insulin gene enhancer sequences. Essential for heart development. Marker of one progenitor cell population that give rise to the outflow tract, right ventricle, a subset of left ventricular cells, and a large number of atrial cells as well, its function is required for these progenitors to contribute to the heart. Controls the expression of FGF and BMP growth factors in this cell population and is required for proliferation and survival of cells within pharyngeal foregut endoderm and adjacent splanchnic mesoderm as well as for migration of cardiac progenitors into the heart.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human Islet 1
抗原种属
Human
基因ID
3670
Uniprot ID
研究领域
Neuroscience, Cardiovascular, Developmental biology, Stem cells
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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