Anti-LEU5 Polyclonal Antibody is a Rabbit antibody targeting LEU5. Anti-LEU5 Polyclonal Antibody can be used in WB.

IgG

Human,Mouse,Rat (predicted:Dog,Pig,Horse,Rabbit,Sheep)

1. Sample:
Liver (Mouse) Lysate at 40 μg
Primary: Anti-LEU5 (TMAB-01062) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 47 kDa
Observed band size: 48 kDa
2. Sample:
Lane 1: Mouse Testis Lysates
Lane 2: Rat Testis Lysates
Lane 3: Rat LympHLysates
Lane 4: Human HL-60 cell Lysates
Lane 5: Human SH-SY5Y cell Lysates
Lane 6: Human HeLa cell Lysates
Primary: Anti-LEU5 (TMAB-01062) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 47 kDa
Observed band size: 47 kDa

WB: 1:500-2000

Polyclonal

KLH conjugated synthetic peptide: human LEU5/RFP2

Human

TRIM13

E3 ubiquitin-protein ligase TRIM13

Cell Cycle Inhibitors,Ubiquitin ligases,Ubiquitylation,Developmental Families,NFkB Pathway

E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. Enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation. Regulates ER stress-induced autophagy, and may act as a tumor suppressor.