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Anti-ARRB1 Antibody (3Y284)

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Anti-ARRB1 Antibody (3Y284)
产品编号 TMAC-00424
别名 β-Arrestin-1, Beta-Arrestin-1, Arrestin β-1, Arrestin Beta-1, ARRB1, ARR1

Anti-ARRB1 Antibody (3Y284) 是一种 Rabbit 抗体,靶向 ARRB1。Anti-ARRB1 Antibody (3Y284) 可用于 WB,ICC/IF,IHC,IP,FCM。

Anti-ARRB1 Antibody (3Y284)

Anti-ARRB1 Antibody (3Y284)

Rating icon 还可以
Anti-ARRB1 Antibody (3Y284)
产品编号 TMAC-00424 别名 β-Arrestin-1, Beta-Arrestin-1, Arrestin β-1, Arrestin Beta-1, ARRB1, ARR1

Anti-ARRB1 Antibody (3Y284) 是一种 Rabbit 抗体,靶向 ARRB1。Anti-ARRB1 Antibody (3Y284) 可用于 WB,ICC/IF,IHC,IP,FCM。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-ARRB1 Antibody (3Y284) is a Rabbit antibody targeting ARRB1. Anti-ARRB1 Antibody (3Y284) can be used in WB,ICC/IF,IHC,IP,FCM.
别名β-Arrestin-1, Beta-Arrestin-1, Arrestin β-1, Arrestin Beta-1, ARRB1, ARR1
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of beta Arrestin 1 on different lysates using anti-beta Arrestin 1 antibody at 1/1,000 dilution. Positive control: Lane 1: PC12, Lane 2: Jurkat.
2. Immunohistochemical analysis of paraffin-embedded human lung tissue using anti-beta Arrestin 1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-beta Arrestin 1 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-beta Arrestin 1 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-beta Arrestin 1 antibody. Counter stained with hematoxylin.
6. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-beta Arrestin 1 antibody. Counter stained with hematoxylin.
7. ICC staining beta Arrestin 1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. ICC staining beta Arrestin 1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
9. ICC staining beta Arrestin 1 in PC12 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
10. Flow cytometric analysis of Hela cells with beta Arrestin 1 antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
推荐剂量
WB: 1:1000-2000; IHC: 1:50-100; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The members of the G protein coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. Members of theβ-Arrestin family regulate receptor binding to G proteins. β-Arrestins have been found to be located at postsynaptic sites, where they are thought to act in concert withβARK (βARK1, also designated GRK 2, orβARK2, also designated GRK 3 to regulate G protein-coupled neurotransmitter receptors. Expression ofβ-Arrestin-1 and b-Arrestin-2 is seen predominantly in spleen and neuronal tissues. It has been shown thatβ-Arrestin-1 expression is modulated by intracellular cAMP, which may be a novel mechanism for the regulation of receptor-mediated responses.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 50 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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