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Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-TrkA (Tyr680/681)。Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody 可用于 WB。
Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-TrkA (Tyr680/681)。Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,235 | 5日内发货 |
产品描述 | Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TrkA (Tyr680/681). Anti-Phospho-TrkA (Tyr680/681) Polyclonal Antibody can be used in WB. |
别名 | TrkA (p-Y680/681), TrkA (p-Tyr680/681), p-TrkA (Y680/681), p-TrkA (Tyr680/681) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of extracts from Jurkat cells treated with starved using Phospho-Trk A (Tyr680/Tyr681) antibody TMAC-04121. The lane on the right is treated with the antigen-specific peptide. |
应用 | |
推荐剂量 | WB: 1:500-1000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC-gamma-1-dependent signaling pathway. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of tyrosine 680/tyrosine 681 (T-D-Y(p)-Y(p)-R-V) derived from Human Trk A |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 87 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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