keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MHI-148 是一种具有肿瘤靶向性的近红外七甲氨酸菁染料,可用于检测、诊断和研究癌症。MHI-148 可被肿瘤细胞的溶酶体和线粒体吸收并积累,但在正常细胞的溶酶体和线粒体不吸收。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
2 mg | ¥ 115 | 现货 | ||
5 mg | ¥ 169 | 现货 | ||
10 mg | ¥ 233 | 现货 | ||
25 mg | ¥ 372 | 现货 | ||
50 mg | ¥ 619 | 现货 | ||
100 mg | ¥ 993 | 现货 |
产品描述 | MHI-148 is a tumor-targeting near-infrared heptamethylenecarbocyanine dye for the detection, diagnosis, and study of cancer.MHI-148 is taken up and accumulates in the lysosomes and mitochondria of tumor cells but is not taken up in the lysosomes and mitochondria of normal cells.MHI-148 is a tumor-targeting near-infrared heptamethylenecarbocyanine dye for the detection and diagnosis of cancer. |
体外活性 |
Compound MHI-148 (10 µM; 1 h) demonstrates notably higher absorption in HT-29 colon carcinoma cells compared to normal NIH3T3 fibroblasts.[1] alongside its capacity for tumor imaging and targeted properties.[1] Compound MHI-148 (0-1.5 µM; 3 days) exhibits only negligible toxicity in both HT-29 and NIH3T3 cells.[1] |
别名 | IR-808 |
分子量 | 764.23 |
分子式 | C42H52BrClN2O4 |
CAS No. | 172971-76-5 |
keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 18.7 mg/mL (24.5 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 1.3085 mL | 6.5425 mL | 13.0851 mL | 32.7127 mL |
5 mM | 0.2617 mL | 1.3085 mL | 2.617 mL | 6.5425 mL | |
10 mM | 0.1309 mL | 0.6543 mL | 1.3085 mL | 3.2713 mL | |
20 mM | 0.0654 mL | 0.3271 mL | 0.6543 mL | 1.6356 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
MHI-148 172971-76-5 MHI148 CompoundMHI148 MHI 148 IR-808 Inhibitor inhibitor inhibit