Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed predominantly nuclei/peri-nuclei localization of TSHR in cancerous tissues but cell membrane localization in non-cancerous parts. Overexpression of TSHR was found in a great majority of HCC tissues and associated with unfavorable prognosis.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
50 μg | ¥ 2,260 | 现货 | ||
100 μg | ¥ 3,880 | 5日内发货 | ||
200 μg | ¥ 6,630 | 5日内发货 | ||
500 μg | ¥ 13,410 | 5日内发货 |
生物活性 | Testing in progress |
产品描述 | Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed predominantly nuclei/peri-nuclei localization of TSHR in cancerous tissues but cell membrane localization in non-cancerous parts. Overexpression of TSHR was found in a great majority of HCC tissues and associated with unfavorable prognosis. |
种属 | Human |
表达系统 | Baculovirus Insect Cells |
标签 | C-His |
蛋白编号 | A0A0A0MTJ0 |
别名 | TSHR, hTSHR-I, TSH Receptor, LGR3, CHNG1 |
蛋白构建 | The Human TSHR (NP_000360.2) (Gly21-Gly413) was expressed with a polyhistidine tag at the C-terminus. |
蛋白纯度 |
> 85 % as determined by SDS-PAGE.
|
分子量 | 46.1 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris, 150 mM NaCl, 10% Glycerol, 1 mM TCEP, pH 7.5. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed predominantly nuclei/peri-nuclei localization of TSHR in cancerous tissues but cell membrane localization in non-cancerous parts. Overexpression of TSHR was found in a great majority of HCC tissues and associated with unfavorable prognosis. |
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TSHR Protein, Human, Recombinant (His) TSHR LGR 3 hTSHR-I LGR-3 TSH Receptor LGR3 CHNG1 CHNG-1 CHNG 1 recombinant recombinant-proteins proteins protein