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Anti-Transferrin Receptor/TFRC Antibody (2H693)

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产品编号 TMAY-03441

Anti-Transferrin Receptor/TFRC Antibody (2H693) 是一种 Rabbit 抗体,靶向 Transferrin Receptor/TFRC。Anti-Transferrin Receptor/TFRC Antibody (2H693) 可用于 IHC-P。

Anti-Transferrin Receptor/TFRC Antibody (2H693)

Anti-Transferrin Receptor/TFRC Antibody (2H693)

Rating icon 还可以
产品编号 TMAY-03441

Anti-Transferrin Receptor/TFRC Antibody (2H693) 是一种 Rabbit 抗体,靶向 Transferrin Receptor/TFRC。Anti-Transferrin Receptor/TFRC Antibody (2H693) 可用于 IHC-P。

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产品介绍

生物活性
产品描述
Anti-Transferrin Receptor/TFRC Antibody (2H693) is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody (2H693) can be used in IHC-P.
Ig Type
Monoclonal Rabbit IgG
克隆号
2H693
交叉反应
Mouse
验证活性
1. Immunochemical staining of mouse TFRC in mouse liver with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.

2. Immunochemical staining of mouse TFRC in mouse kidney with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.

3. Immunochemical staining of mouse TFRC in mouse small intestine with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.
应用
IHC-P
推荐剂量
IHC-P: 1:100-1:500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Transferrin Receptor / TFRC (rM Transferrin Receptor / TFRC; TMPY-02294; Q62351; Cys89-Phe763).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Mouse Transferrin Receptor / TFRC Protein (TMPY-02294)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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