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Anti-Phospho-C-ABL/ABL1 (Tyr412) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-C-ABL/ABL1 (Tyr412)。Anti-Phospho-C-ABL/ABL1 (Tyr412) Polyclonal Antibody 可用于 WB。
Anti-Phospho-C-ABL/ABL1 (Tyr412) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-C-ABL/ABL1 (Tyr412)。Anti-Phospho-C-ABL/ABL1 (Tyr412) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,235 | 5日内发货 |
产品描述 | Anti-Phospho-C-ABL/ABL1 (Tyr412) Polyclonal Antibody is a Rabbit antibody targeting Phospho-C-ABL/ABL1 (Tyr412). Anti-Phospho-C-ABL/ABL1 (Tyr412) Polyclonal Antibody can be used in WB. |
别名 | p-C-ABL/ABL1 (Y412), p-C-ABL/ABL1 (Tyr412), C-ABL/ABL1 (p-Y412), C-ABL/ABL1 (p-Tyr412) |
Ig Type | IgG |
交叉反应 | Human |
应用 | |
推荐剂量 | WB: 1:1000-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
性状 | Liquid |
缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
研究背景 | ABL proto-oncogene 1, non-receptor tyrosine kinase(ABL1) Homo sapiens This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. [pr |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human c-Abl around the phosphorylation site of Tyr412 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 140 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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