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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-Galectin-1 Antibody (6V681)

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货号 TMAY-03789

别名 lectin, galactoside-binding, soluble, 1, GBP, Galectin-1, GAL1

Anti-Galectin-1 Antibody (6V681) 是一种 Mouse 抗体，靶向 Galectin-1。Anti-Galectin-1 Antibody (6V681) 可用于 ELISA。

Anti-Galectin-1 Antibody (6V681)

Anti-Galectin-1 Antibody (6V681)

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货号 TMAY-03789 别名 lectin, galactoside-binding, soluble, 1, GBP, Galectin-1, GAL1

Anti-Galectin-1 Antibody (6V681) 是一种 Mouse 抗体，靶向 Galectin-1。Anti-Galectin-1 Antibody (6V681) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,679
5日内发货
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产品介绍

生物活性
产品描述
Anti-Galectin-1 Antibody (6V681) is a Mouse antibody targeting Galectin-1. Anti-Galectin-1 Antibody (6V681) can be used in ELISA.
别名lectin, galactoside-binding, soluble, 1, GBP, Galectin-1, GAL1
Ig Type
Mouse IgG1
克隆号
6V681
反应种属
Rat
特异性
Rat Galectin-1/LGALS1
应用ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat Galectin-1 / LGALS1 (rR Galectin-1 / LGALS1; P11762; Ala2-Glu135). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Galectin-1 (Gal-1, GAL1), is a member of the galectins, a family of animal lectins ranging from Caenorhabditis elegans to humans, which is defined by their affinity for beta-galactosides and by significant sequence similarity in the carbohydrate-binding site. It is a homodimer with a subunit molecular mass of 14.5 kDa, which contains six cysteine residues per subunit. The cysteine residues should be in a free state to maintain a molecular structure that is capable of showing lectin activity. This endogenous lectin widely expressed at sites of inflammation and tumor growth has been postulated as an attractive immunosuppressive agent to restore immune cell tolerance and homeostasis in autoimmune and inflammatory settings. On the other hand, galectin-1 contributes to different steps of tumor progression including cell adhesion, migration, and tumor-immune escape, suggesting that blockade of galectin-1 might result in therapeutic benefits in cancer. Several potential glycoprotein ligands for galectin-1 have been identified, including lysosome-associated membrane glycoproteins and fibronectin, laminin, as well as T-cell glycoproteins CD43 and CD45. Evidence points to Gal-1 and its ligands as one of the master regulators of such immune responses as T-cell homeostasis and survival, T-cell immune disorders, inflammation, and allergies as well as host-pathogen interactions.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Rat Galectin-1 / LGALS1 Protein
抗原种属
Rat
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.
存储-20°C for 1 year

计算器

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关键词

GAL-1GAL 1
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