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Anti-GRIN1 Antibody (5R681)

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产品编号 TMAB-00813

别名 N-methyl-D-aspartate receptor subunit NR1 (NMD-R1;hNR1), NMDAR1, NMDA 1, GRIN1, Glutamate receptor ionotropic, NMDA 1, Glutamate [NMDA] receptor subunit zeta-1, GluN1

Anti-GRIN1 Antibody (5R681) 是一种 Rabbit 抗体，靶向 GRIN1。Anti-GRIN1 Antibody (5R681) 可用于 IF,IHC-Fr,IHC-P,WB。

Anti-GRIN1 Antibody (5R681)

Anti-GRIN1 Antibody (5R681)

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产品编号 TMAB-00813 别名 N-methyl-D-aspartate receptor subunit NR1 (NMD-R1;hNR1), NMDAR1, NMDA 1, GRIN1, Glutamate receptor ionotropic, NMDA 1, Glutamate [NMDA] receptor subunit zeta-1, GluN1

Anti-GRIN1 Antibody (5R681) 是一种 Rabbit 抗体，靶向 GRIN1。Anti-GRIN1 Antibody (5R681) 可用于 IF,IHC-Fr,IHC-P,WB。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-GRIN1 Antibody (5R681) is a Rabbit antibody targeting GRIN1. Anti-GRIN1 Antibody (5R681) can be used in IF,IHC-Fr,IHC-P,WB.
别名N-methyl-D-aspartate receptor subunit NR1 (NMD-R1;hNR1), NMDAR1, NMDA 1, GRIN1, Glutamate receptor ionotropic, NMDA 1, Glutamate [NMDA] receptor subunit zeta-1, GluN1
Ig Type
IgG
克隆号
5R681
交叉反应
Rat,Mouse,Human
验证活性
1. 25 μg total protein per Lane of various lysates probed with NMDAR1 monoclonal antibody, unconjugated (TMAB-00813) at 1:2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.
2. Paraformaldehyde-fixed, paraffin embedded Mouse Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with NMDAR1 Monoclonal Antibody, Unconjugated (TMAB-00813) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Rat Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with NMDAR1 Monoclonal Antibody, Unconjugated (TMAB-00813) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded Mouse Cerebellum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with NMDAR1 Monoclonal Antibody, Unconjugated (TMAB-00813) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
5. Paraformaldehyde-fixed, paraffin embedded Human Cerebellum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with NMDAR1 Monoclonal Antibody, Unconjugated (TMAB-00813) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
6. Paraformaldehyde-fixed, paraffin embedded Human Left Parietal Lobe; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with NMDAR1 Monoclonal Antibody, Unconjugated (TMAB-00813) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
应用IFIHC-FrIHC-PWB
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Note=Enriched in post-synaptic plasma membrane and post-synaptic densities.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
A synthesized peptide: human GluN1
抗原种属
Human
基因名称
GRIN1
基因ID
2902
蛋白名称
Glutamate receptor ionotropic, NMDA 1
Uniprot ID
Q05586
研究领域
Growth Cone,Neurogenesis
功能
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.
化学信息
分子量Theoretical: 103 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

NMD-R1NMDR1NMDAR 1NMDA1GRIN 1Glutamate [NMDA] receptor subunit ζ-1GluN 1

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