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Anti-RPE65 Antibody (2C823)
还可以产品编号 TMAH-01051
Anti-RPE65 Antibody (2C823) 是一种抗体，靶向 RPE65。Anti-RPE65 Antibody (2C823) 可用于 ELISA, IHC。
Anti-RPE65 Antibody (2C823)
Anti-RPE65 Antibody (2C823)
还可以产品编号 TMAH-01051
Anti-RPE65 Antibody (2C823) 是一种抗体，靶向 RPE65。Anti-RPE65 Antibody (2C823) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,300 | 5日内发货 | |
| 100 μL | ¥ 2,195 | 5日内发货 |
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产品介绍
生物活性
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抗原信息
| 产品描述 | Anti-RPE65 Antibody (2C823) is an antibody targeting RPE65. Anti-RPE65 Antibody (2C823) can be used in ELISA, IHC. |
| Ig Type | Rabbit IgG |
| 克隆号 | 2C823 |
| 交叉反应 | Human |
| 验证活性 | IHC image of TMAH-01051 diluted at 1:100 and staining in paraffin-embedded human eye tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| 应用 | ELISA, IHC |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cytoplasm. Cell membrane; Lipid-anchor. Microsome membrane. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Critical isomerohydrolase in the retinoid cycle involved in regeneration of 11-cis-retinal, the chromophore of rod and cone opsins. Catalyzes the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol which is further oxidized by 11-cis retinol dehydrogenase to 11-cis-retinal for use as visual chromophore. Essential for the production of 11-cis retinal for both rod and cone photoreceptors. Also capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human RPE65 |
| 抗原种属 | Human |
| 基因ID | 6121 |
| Uniprot ID | |
| 研究领域 | Neuroscience, Cancer, Tags & Cell Markers, Metabolism, Signal transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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