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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-IL-1R2 Polyclonal Antibody

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货号 TMAB-07626

Anti-IL-1R2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 IL-1R2。Anti-IL-1R2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

Anti-IL-1R2 Polyclonal Antibody

Anti-IL-1R2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-07626

Anti-IL-1R2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 IL-1R2。Anti-IL-1R2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL-1R2 Polyclonal Antibody is a Rabbit antibody targeting IL-1R2. Anti-IL-1R2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Dog)
应用WBIHC-PIHC-FrIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoform Short: Secreted. Isoform Long: Cell membrane; Single-pass type I membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4(IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated synthetic peptide: human IL-1R II
抗原种属
Human
基因名称
IL1R2
基因ID
7850
蛋白名称
Interleukin-1 receptor type 2
Uniprot ID
P27930
功能
Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
化学信息
分子量Theoretical: 44 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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