Name: CXCL7 Protein, Cynomolgus, Recombinant (mFc)
Brand: TargetMol
SKU: TMPY-03043
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 458

6-8日内发货

10 μg

¥ 747

6-8日内发货

20 μg

¥ 1,230

5日内发货

50 μg

¥ 2,830

5日内发货

生物活性

产品描述	CXCL7 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 34.3 kDa and the accession number is F6SCP6.
生物活性	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	Pro-platelet basic protein (PPBP) is also known as Chemokine (C-X-C motif) ligand 7 (CXCL7) and nucleosome assembly protein (Nap-2). Nap-2 / PPBP / CXCL7 is released in large amounts from platelets following their activation and is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. Nap-2 / PPBP / CXCL7 has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. Nap-2 is a ligand for CXCR1 and CXCR2, and Nap-2, Nap-2 (73), Nap-2 (74), Nap-2 (1-66), and most potent Nap-2 (1-63) are chemoattractants and activators for neutrophils.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
种属	Cynomolgus
表达系统	HEK293 Cells
标签	N-mFc
蛋白编号	F6SCP6
蛋白构建	A DNA sequence encoding the cynomolgus PPBP (F6SCP6) (Thr59-Asp128) was expressed fused with the Fc region of mouse IgG1 at the N-terminus. Predicted N terminal: Asp
蛋白纯度	> 90 % as determined by SDS-PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	34.3 kDa (predicted); 38 kDa (reducing conditions)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

CXCL7 Protein, Cynomolgus, Recombinant (mFc)

CXCL7 Protein, Cynomolgus, Recombinant (mFc)

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