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Anti-TAL-1 Antibody (7H409)
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产品编号 TMAC-03961
别名 TCL5, TCL 5, T-cell leukemia/lymphoma protein 5, T-cell acute lymphocytic leukemia protein 1, TAL1_HUMAN, tal1, TAL 1 protein, Tal 1 product, Tal 1, T cell leukemia/lymphoma 5 protein, T cell acute lymphocytic leukemia 1 protein, T cell acute lymphocytic leukemia 1, Stem cell protein, STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR, SCL, OTTHUMP00000009564, OTTHUMP00000009563, Class A basic helix-loop-helix protein 17, bHLHa17
Anti-TAL-1 Antibody (7H409) 是一种 Mouse 抗体，靶向 TAL-1。Anti-TAL-1 Antibody (7H409) 可用于 WB,IP,IF。
Anti-TAL-1 Antibody (7H409)
Anti-TAL-1 Antibody (7H409)
还可以产品编号 TMAC-03961 别名 TCL5, TCL 5, T-cell leukemia/lymphoma protein 5, T-cell acute lymphocytic leukemia protein 1, TAL1_HUMAN, tal1, TAL 1 protein, Tal 1 product, Tal 1, T cell leukemia/lymphoma 5 protein, T cell acute lymphocytic leukemia 1 protein, T cell acute lymphocytic leukemia 1, Stem cell protein, STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR, SCL, OTTHUMP00000009564, OTTHUMP00000009563, Class A basic helix-loop-helix protein 17, bHLHa17
Anti-TAL-1 Antibody (7H409) 是一种 Mouse 抗体，靶向 TAL-1。Anti-TAL-1 Antibody (7H409) 可用于 WB,IP,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,980 | 5日内发货 | |
| 100 μL | ¥ 2,995 | 5日内发货 |
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| 产品描述 | Anti-TAL-1 Antibody (7H409) is a Mouse antibody targeting TAL-1. Anti-TAL-1 Antibody (7H409) can be used in WB,IP,IF. |
| 别名 | TCL5, TCL 5, T-cell leukemia/lymphoma protein 5, T-cell acute lymphocytic leukemia protein 1, TAL1_HUMAN, tal1, TAL 1 protein, Tal 1 product, Tal 1, T cell leukemia/lymphoma 5 protein, T cell acute lymphocytic leukemia 1 protein, T cell acute lymphocytic leukemia 1, Stem cell protein, STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR, SCL, OTTHUMP00000009564, OTTHUMP00000009563, Class A basic helix-loop-helix protein 17, bHLHa17 |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of TAL1 expression in non-transfected (A) and human TAL1 transfected (B) 293T whole cell lysates and CCRF-CEM (C), Jurkat (D) and K-562 (E) nuclear extracts. |
| 应用 | |
| 推荐剂量 | WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic coexpression of TAL1 and the catalytic subunit of casein kinase IIα, a serine/ threonine protein kinase known to modulate the activity of other βHLH transcription factors. |
| 偶联 | Unconjugated |
| 免疫原 | Peptide |
| Uniprot ID |
| 分子量 | Theoretical: 42 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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