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Anti-B7-1 Antibody-APC (5N350)
还可以产品编号 TMAY-03297A
Anti-B7-1 Antibody-APC (5N350) 是一种 APC-conjugated Rabbit 抗体，靶向 B7-1。Anti-B7-1 Antibody-APC (5N350) 可用于 FCM。
Anti-B7-1 Antibody-APC (5N350)
Anti-B7-1 Antibody-APC (5N350)
还可以产品编号 TMAY-03297A
Anti-B7-1 Antibody-APC (5N350) 是一种 APC-conjugated Rabbit 抗体，靶向 B7-1。Anti-B7-1 Antibody-APC (5N350) 可用于 FCM。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-B7-1 Antibody-APC (5N350) is a APC-conjugated Rabbit antibody targeting B7-1. Anti-B7-1 Antibody-APC (5N350) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 5N350 |
| 交叉反应 | Mouse |
| 验证活性 | Flow cytometric analysis of Mouse CD80 expression on LPS-stimulated BABL/c splenocytes. Cells were stained with APC-conjugated anti-Mouse CD80. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD80/B7-1 (rM CD80/B7-1; TMPY-02307; Q00609-1; Met1-Lys245) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. As costimulatory ligands, B7-1 which exists predominantly as dimer and the related protein B7-2, interact with the costimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus constitute one of the dominant pathways that regulate T cell activation and tolerance, cytokine production, and the generation of CTL. The B7/CD28/CTLA4 pathway has the ability to both positively and negatively regulate immune responses. CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| 偶联 | APC |
| 其他可选修饰符 | Unconjugated/PE |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Mouse CD80/B7-1 Protein (TMPY-02307) |
| 抗原种属 | Mouse |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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