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Ephrin A1/EFNA1 Protein, Mouse, Recombinant (His)

产品编号 TMPY-01723

Ephrin A1/EFNA1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is P52793.

Ephrin A1/EFNA1 Protein, Mouse, Recombinant (His)

产品编号 TMPY-01723

Ephrin A1/EFNA1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is P52793.

规格	价格	库存	数量
100 μg	¥ 2,940	5日内发货

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产品信息

生物活性	Measured by its ability to compete with mouse EFNA1 for binding to immobilized mouse EphA2 in a functional ELISA assay.
产品描述	Ephrin A1/EFNA1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is P52793.
种属	Mouse
表达系统	HEK293 Cells
标签	C-His
蛋白编号	P52793
别名	Lerk1,Eplg1,Epl1,ephrin-A1,Efl1,B61,AI325262
蛋白构建	A DNA sequence encoding the mouse EFNA1 (NP_034237.3) without the pro peptide (Met 1-Ser 182) was fused with a polyhistidine tag at the C-terminus. Predicted N terminal: Asp 19
蛋白纯度	> 97 % as determined by SDS-PAGE
分子量	20 kDa (predicted); 27 kDa (reducing condition, due to glycosylation)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	EPH-related receptor tyrosine kinase ligand 1 (abbreviated as Ephrin-A1) also known as ligand of eph-related kinase 1 or EFNA1, is a member of the ephrin (EPH) family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin-A1/EFNA1 and its Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins. Ephrin-A1 and one of its receptor EphA2 were expressed in xenograft endothelial cells and also tumor cells and play a role in human cancers, at least in part by influencing tumor neovascularization.