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Anti-Mart-1 Antibody (2F603)

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货号 TMAB-08618

Anti-Mart-1 Antibody (2F603) 是一种 Mouse 抗体,靶向 Mart-1。Anti-Mart-1 Antibody (2F603) 可用于 IHC-P,IHC-Fr,IF,WB。

Anti-Mart-1 Antibody (2F603)

Anti-Mart-1 Antibody (2F603)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08618

Anti-Mart-1 Antibody (2F603) 是一种 Mouse 抗体,靶向 Mart-1。Anti-Mart-1 Antibody (2F603) 可用于 IHC-P,IHC-Fr,IF,WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
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产品介绍


生物活性
产品描述
Anti-Mart-1 Antibody (2F603) is a Mouse antibody targeting Mart-1. Anti-Mart-1 Antibody (2F603) can be used in IHC-P,IHC-Fr,IF,WB.
Ig Type
IgG
克隆号
2F603
反应种属
Human
应用IHC-PIHC-FrIFWB
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Endoplasmic reticulum membrane; Single-pass type III membrane protein. Golgi apparatus. Golgi apparatus, trans-Golgi network membrane. Melanosome. Note=Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post-Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation.
组织特异性Expression is restricted to melanoma and melanocyte cell lines and retina.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液PBS containing 50% Glycerol, 0.5% BSA and 0.02% Proclin300.
浓度1mg/ml
研究背景Melan A, a product of the MART-1 gene, is a melanocyte differentiation marker recognized by autologous cytotoxic T lymphocytes. Other melanoma-associated markers recognized by autologous cytotoxic T cells are reported to include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1 and GAGE-1. The analysis of these different molecules and their expression in individual melanomas may be of help in the study of their particular molecular roles in melanocyte differentiation and tumorigenesis.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Mart-1
抗原种属
Human
基因名称
MLANA
基因ID
蛋白名称
Melanoma antigen recognized by T-cells 1
Uniprot ID
功能
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
化学信息
分子量Theoretical: 13 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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