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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RAB5A Antibody (9G171)

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货号 TMAB-12003

Anti-RAB5A Antibody (9G171) 是一种 Rabbit 抗体，靶向 RAB5A。Anti-RAB5A Antibody (9G171) 可用于 WB,IHC-P,IHC-Fr,IF,ICC/IF。

Anti-RAB5A Antibody (9G171)

Anti-RAB5A Antibody (9G171)

一键复制产品信息
Rating icon 还可以
货号 TMAB-12003

Anti-RAB5A Antibody (9G171) 是一种 Rabbit 抗体，靶向 RAB5A。Anti-RAB5A Antibody (9G171) 可用于 WB,IHC-P,IHC-Fr,IF,ICC/IF。

规格价格库存数量
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,495
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

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产品描述
Anti-RAB5A Antibody (9G171) is a Rabbit antibody targeting RAB5A. Anti-RAB5A Antibody (9G171) can be used in WB,IHC-P,IHC-Fr,IF,ICC/IF.
Ig Type
IgG
克隆号
9G171
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIFICC/IF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Melanosome.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Rab5-related subfamily. This subfamily includes Rab5 and Rab22 of mammals, Ypt51/Ypt52/Ypt53 of yeast, and RabF of plants. The members of this subfamily are involved in endocytosis and endocytic-sorting pathways. In mammals, Rab5 GTPases localize to early endosomes and regulate fusion of clathrin-coated vesicles to early endosomes and fusion between early endosomes. In yeast, Ypt51p family members similarly regulate membrane trafficking through prevacuolar compartments. GTPase activating proteins (GAPs) interact with GTP-bound Rab and accelerate the hydrolysis of GTP to GDP. Guanine nucleotide exchange factors (GEFs) interact with GDP-bound Rabs to promote the formation of the GTP-bound state. Rabs are further regulated by guanine nucleotide dissociation inhibitors (GDIs), which facilitate Rab recycling by masking C-terminal lipid binding and promoting cytosolic localization. Most Rab GTPases contain a lipid modification site at the C-terminus, with sequence motifs CC, CXC, or CCX. Lipid binding is essential for membrane attachment, a key feature of most Rab proteins. Due to the presence of truncated sequences in this CD, the lipid modification site is not available for annotation.
抗原信息
免疫原
A synthesized peptide: human Rab5A
抗原种属
Human
基因名称
RAB5A
基因ID
5868
蛋白名称
Ras-related protein Rab-5A
Uniprot ID
P20339
功能
Binds EEA1. Interacts with RIN1 and GAPVD1, which regulate its pathway, probably by acting as a GEF. Interacts with ALS2CL, RABEP1, SUN2, ZFYVE20 and RUFY1. Interacts with SGSM1 and SGSM3. Interacts with PIK3CB.
化学信息
分子量Theoretical: 22 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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