购物车
- 全部删除
- 您的购物车当前为空
Anti-ICAM-2/CD102 Antibody (5Q635) 是一种 Rabbit 抗体,靶向 ICAM-2/CD102。Anti-ICAM-2/CD102 Antibody (5Q635) 可用于 WB。
Anti-ICAM-2/CD102 Antibody (5Q635) 是一种 Rabbit 抗体,靶向 ICAM-2/CD102。Anti-ICAM-2/CD102 Antibody (5Q635) 可用于 WB。
产品描述 | Anti-ICAM-2/CD102 Antibody (5Q635) is a Rabbit antibody targeting ICAM-2/CD102. Anti-ICAM-2/CD102 Antibody (5Q635) can be used in WB. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 5Q635 |
交叉反应 | Human |
验证活性 | Anti-ICAM2 rabbit monoclonal antibody at 1:500 dilution. -Lane A: HelaS3 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:31 kDa. -Observed band size:37 kDa |
应用 | WB |
推荐剂量 | WB: 1:500-1:1000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human ICAM-2 / CD102 (rh ICAM-2 / CD102; TMPY-01418; NP_000864.2; Met1-Gln223). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Intercellular adhesion molecule 2 (ICAM-2, CD102), belongs to the ICAM family consisting of three members identified as ligands for integrin receptors. It is a type I transmembrane glycoprotein with two Ig-like C2-type domains and binds to the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). As the second ligand of leukocyte function-associated antigen-1, ICAM-2 functions as a costimulatory molecule for effector cells. ICAM-2 is mainly expressed on vascular endothelial and hematopoietic cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocyte with other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity, and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relationship with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in the diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment. |
偶联 | Unconjugated |
免疫原 | Recombinant Human ICAM-2 / CD102 protein (TMPY-01418) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
评论内容