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Anti-ICAM-2/CD102 Antibody (5Q635)

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产品编号 TMAY-00624

Anti-ICAM-2/CD102 Antibody (5Q635) 是一种 Rabbit 抗体,靶向 ICAM-2/CD102。Anti-ICAM-2/CD102 Antibody (5Q635) 可用于 WB。

Anti-ICAM-2/CD102 Antibody (5Q635)

Anti-ICAM-2/CD102 Antibody (5Q635)

Rating icon 还可以
产品编号 TMAY-00624

Anti-ICAM-2/CD102 Antibody (5Q635) 是一种 Rabbit 抗体,靶向 ICAM-2/CD102。Anti-ICAM-2/CD102 Antibody (5Q635) 可用于 WB。

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产品介绍

生物活性
产品描述
Anti-ICAM-2/CD102 Antibody (5Q635) is a Rabbit antibody targeting ICAM-2/CD102. Anti-ICAM-2/CD102 Antibody (5Q635) can be used in WB.
Ig Type
Monoclonal Rabbit IgG
克隆号
5Q635
交叉反应
Human
验证活性
Anti-ICAM2 rabbit monoclonal antibody at 1:500 dilution.

-Lane A: HelaS3 Whole Cell lysate.

-Lysates/proteins at 30 μg per lane.

-Secondary

-Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

-Developed using the Odyssey technique.

-Performed under reducing conditions.

-Predicted band size:31 kDa.

-Observed band size:37 kDa
应用
WB
推荐剂量
WB: 1:500-1:1000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human ICAM-2 / CD102 (rh ICAM-2 / CD102; TMPY-01418; NP_000864.2; Met1-Gln223).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Intercellular adhesion molecule 2 (ICAM-2, CD102), belongs to the ICAM family consisting of three members identified as ligands for integrin receptors. It is a type I transmembrane glycoprotein with two Ig-like C2-type domains and binds to the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). As the second ligand of leukocyte function-associated antigen-1, ICAM-2 functions as a costimulatory molecule for effector cells. ICAM-2 is mainly expressed on vascular endothelial and hematopoietic cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocyte with other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity, and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relationship with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in the diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human ICAM-2 / CD102 protein (TMPY-01418)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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4个月前
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