购物车
Nectin-3 Protein, Human, Recombinant (His)

Nectin-3 Protein, Human, Recombinant (His)

产品编号 TMPY-01154
别名: PRR3, FLJ90624, PVRL3, poliovirus receptor-related 3, CDw113, PPR3, CD113, PVRR3, DKFZp566B0846, nectin-3

Nectin-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.3 kDa and the accession number is Q9NQS3-1.

TargetMol的所有产品和服务仅用于科学研究,不能被用于人体,我们也不向个人提供产品和服务。
TargetMol
Nectin-3 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
100 μg ¥ 3,820 5日内发货
1 mg ¥ 24,900 5日内发货
药物设计专题培训
千万补贴 助力科研
BCA蛋白浓度测定试剂盒限时半价
产品目录号及名称: Nectin-3 Protein, Human, Recombinant (His) (TMPY-01154)
点击图片重新获取验证码
更多批次查询请联系客服
生物活性
技术参数
产品性质
参考文献
生物活性 Immobilized Human Nectin 3 His at 2 μg/mL (100 μL/well) can bind Human PVRL1/NECTIN1 hFc , the EC50 of Human PVRL1/NECTIN1 hFc is 3-24 ng/mL.
产品描述 Nectin-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.3 kDa and the accession number is Q9NQS3-1.
种属 Human
表达系统 HEK293 Cells
标签 C-His
蛋白编号 Q9NQS3-1
别名 PRR3, FLJ90624, PVRL3, poliovirus receptor-related 3, CDw113, PPR3, CD113, PVRR3, DKFZp566B0846, nectin-3
蛋白构建 The extracellular domain of Human PVRL3 (NP_056295.1) (Met 1-Asp 400) was expressed, with a polyhistidine tag at the C-terminus.
蛋白纯度 > 98 % as determined by SDS-PAGE
分子量 39.3 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 Poliovirus receptor-related 3 (PVRL3), also known as Nectin-3 and CD113, is a member of the nectin family. PVRL3/Nectin-3 is an 83 kDa, type I transmembrane glycoprotein. Its precursor is 549 amino acids (aa) in length and contains an extended signal sequence of 57 aa, an extracellular domain (ECD) of 347 aa, a transmembrane segment of 21 aa, and a cytoplasmic region of 124 aa. Nectin-3 has three splicing variants, nectin-3alpha (biggest), -3beta (middle), and -3gamma (smallest). It is predominantly expressed in testis and placenta as well as in various cell lines, including epithelial cell lines. PVRL3/Nectin-3 plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/Nectin-2 at Sertoli-spermatid junctions. PVRL3/Nectin-3 is thus involved in the formation of cell-cell junctions, including adherens junctions and synapses. It has been shown to induce endocytosis-mediated down-regulation of PVR from the cell surface, resulting in the reduction of cell movement and proliferation.

TargetMol Library Books参考文献

TargetMol Protein Calculator计算器

复溶计算器
重组蛋白稀释计算器
比活力计算器
=
÷
X
=
X
(Unit/mg)
= 106 ÷
ng/mL

bottom

技术支持

您可能有的问题的答案可以在重组蛋白操作手册中找到

Keywords

Nectin-3 Protein, Human, Recombinant (His) CD-113 FLJ 90624 PRR3 FLJ-90624 FLJ90624 PVRL3 DKFZp566B 0846 PRR 3 poliovirus receptor-related 3 CD 113 CDw113 DKFZp566B-0846 PPR 3 PPR-3 PPR3 PVRR-3 PVRL 3 PRR-3 PVRL-3 CD113 PVRR3 DKFZp566B0846 PVRR 3 nectin-3 recombinant recombinant-proteins proteins protein

 

TargetMol Loading
陶术
生物
TargetMol®中国区唯一合作伙伴
点击进入陶术生物官网陶术生物
联系我们
400-820-0310

上海市静安区江场三路238号8楼