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Anti-alpha Actinin 4 Antibody (9X533)

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货号 TMAB-02462

Anti-alpha Actinin 4 Antibody (9X533) 是一种 Rabbit 抗体，靶向 alpha Actinin 4。Anti-alpha Actinin 4 Antibody (9X533) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

Anti-alpha Actinin 4 Antibody (9X533)

Anti-alpha Actinin 4 Antibody (9X533)

一键复制产品信息
Rating icon 还可以
货号 TMAB-02462

Anti-alpha Actinin 4 Antibody (9X533) 是一种 Rabbit 抗体，靶向 alpha Actinin 4。Anti-alpha Actinin 4 Antibody (9X533) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

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产品描述
Anti-alpha Actinin 4 Antibody (9X533) is a Rabbit antibody targeting alpha Actinin 4. Anti-alpha Actinin 4 Antibody (9X533) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
克隆号
9X533
反应种属
Human,Mouse
应用WBIHC-PIHC-FrICC/IFIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Colocalizes with actin stress fibers. Nuclear translocation can be induced by the PI3 kinase inhibitor wortmannin or by cytochalasin D. Exclusively localized in the nucleus in a limited number of cell lines (breast cancer cell line MCF-7, oral floor cancer IMC-2, and bladder cancer KU-7).
组织特异性Widely expressed.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human alpha Actinin 4
抗原种属
Human
基因名称
ACTN4
基因ID
81
蛋白名称
alpha-actinin-4
Uniprot ID
O43707
功能
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.
化学信息
分子量Theoretical: 105 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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