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MZB1/PERP1 Protein, Human, Recombinant (His)

MZB1/PERP1 Protein, Human, Recombinant (His)

产品编号 TMPY-03630
别名: MEDA-7, marginal zone B and B1 cell-specific protein, pERp1, HSPC190, PACAP

MZB1 (Marginal Zone B And B1 Cell Specific Protein, also known as MEDA-7 and pERp1) is a Protein Coding gene. MZB1 is a B-cell-specific and endoplasmic reticulum (ER)-localized protein implicated in antibody secretion and integrin-mediated cell adhesion. MZB1 is important for B cell function as a key regulator of antibody secretion, calcium homeostasis, and adhesion. MZB1 may play a central role in B cell neoplasms and is a potential target for future therapeutic interventions. Low MZB1 expression was an independent prognostic factor for recurrence after curative gastrectomy and was associated significantly with increased hematogenous recurrence. MZB1 acts as a suppressor of gastric cancer (GC). Low MZB1 expression in the primary GC tissue is predictive of recurrence after curative resection.

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MZB1/PERP1 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
100 μg ¥ 4,470 现货
200 μg ¥ 7,630 5日内发货
500 μg ¥ 15,450 5日内发货
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产品目录号及名称: MZB1/PERP1 Protein, Human, Recombinant (His) (TMPY-03630)
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产品描述 MZB1 (Marginal Zone B And B1 Cell Specific Protein, also known as MEDA-7 and pERp1) is a Protein Coding gene. MZB1 is a B-cell-specific and endoplasmic reticulum (ER)-localized protein implicated in antibody secretion and integrin-mediated cell adhesion. MZB1 is important for B cell function as a key regulator of antibody secretion, calcium homeostasis, and adhesion. MZB1 may play a central role in B cell neoplasms and is a potential target for future therapeutic interventions. Low MZB1 expression was an independent prognostic factor for recurrence after curative gastrectomy and was associated significantly with increased hematogenous recurrence. MZB1 acts as a suppressor of gastric cancer (GC). Low MZB1 expression in the primary GC tissue is predictive of recurrence after curative resection.
种属 Human
表达系统 HEK293
标签 His
蛋白编号 Q8WU39-1
别名 MEDA-7, marginal zone B and B1 cell-specific protein, pERp1, HSPC190, PACAP
蛋白构建 A DNA sequence encoding the human MGC29506 (Q8WU39-1) (Met 1-Thr 185) was expressed with a polyhistidine tag at the C-terminus.
蛋白纯度 > 95 % as determined by SDS-PAGE

TargetMol

分子量 Approxiamtely 19.4 kDa
内毒素 < 1.0 EU per μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from sterile PBS, PH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
复溶方法 A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

运输方式

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

研究背景 MZB1 (Marginal Zone B And B1 Cell Specific Protein, also known as MEDA-7 and pERp1) is a Protein Coding gene. MZB1 is a B-cell-specific and endoplasmic reticulum (ER)-localized protein implicated in antibody secretion and integrin-mediated cell adhesion. MZB1 is important for B cell function as a key regulator of antibody secretion, calcium homeostasis, and adhesion. MZB1 may play a central role in B cell neoplasms and is a potential target for future therapeutic interventions. Low MZB1 expression was an independent prognostic factor for recurrence after curative gastrectomy and was associated significantly with increased hematogenous recurrence. MZB1 acts as a suppressor of gastric cancer (GC). Low MZB1 expression in the primary GC tissue is predictive of recurrence after curative resection.

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Keywords

MZB1/PERP1 Protein, Human, Recombinant (His) MEDA-7 marginal zone B and B1 cell-specific protein pERp1 MEDA 7 HSPC-190 HSPC190 HSPC 190 PACAP MEDA7 recombinant recombinant-proteins proteins protein

 

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