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Anti-Fetuin A Antibody (9X970)

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货号 TMAY-00604

别名 α-2-HS-glycoprotein, alpha-2-HS-glycoprotein

Anti-Fetuin A Antibody (9X970) 是一种 Rabbit 抗体,靶向 Fetuin A。Anti-Fetuin A Antibody (9X970) 可用于 ELISA,ELISA(Det)。

Anti-Fetuin A Antibody (9X970)

Anti-Fetuin A Antibody (9X970)

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Rating icon 还可以
货号 TMAY-00604 别名 α-2-HS-glycoprotein, alpha-2-HS-glycoprotein

Anti-Fetuin A Antibody (9X970) 是一种 Rabbit 抗体,靶向 Fetuin A。Anti-Fetuin A Antibody (9X970) 可用于 ELISA,ELISA(Det)。

规格价格库存数量
20 μL
¥ 790
5日内发货
100 μL
¥ 2,284
5日内发货
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产品介绍


生物活性
产品描述
Anti-Fetuin A Antibody (9X970) is a Rabbit antibody targeting Fetuin A. Anti-Fetuin A Antibody (9X970) can be used in ELISA,ELISA(Det).
别名α-2-HS-glycoprotein, alpha-2-HS-glycoprotein
Ig Type
Rabbit IgG
克隆号
9X970
反应种属
Human
特异性
Human Fetuin A/FETUA
No cross-reactivity in ELISA with
Human Cystatin-C
Human Cystatin-E
Mouse Fetain-A
应用ELISAELISA(Det)
推荐剂量
ELISA: 1:5000-1:10000; ELISA(Det): 1:1000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human Fetuin-A / AHSG (rh Fetuin-A; TMPY-00801; NP_001613.2; Met 1-Val 367) .
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Fetuin-A, also known as Alpha-2-HS-Glycoprotein (AHSG), belongs to the Fetuin family, is a plasma binding protein, and is more abundant in fetal than adult blood. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. Fetuins are carrier proteins like albumin. Fetuin-A forms soluble complexes with calcium and phosphate and thus is a carrier of otherwise insoluble calcium phosphate. Thus Fetuin-A is a potent inhibitor of pathological calcification. The circulating levels of fetuin-A, a well-described inhibitor of calcification, regulate the cell-dependent process of osteogenesis. The low circulating fetuin-A levels are associated with a greater prevalence and/or severity of Vascular calcification (VC) and increased risk for all-cause and cardiovascular mortality. However, high circulating fetuin-A levels appear to induce insulin resistance and, in non-dialyzed subjects with diabetic nephropathy, are directly related to VC burden. The emerging role of fetuin-A deficiency as a risk factor in dialysis patients was documented in cross-sectional studies demonstrating a significant correlation with all-cause and cardiovascular mortality. Additionally, Human fetuin-A is a negative acute phase protein involved in inflammatory diseases, thus being a potential physiological regulator of meprin activity. Fetuin-A is a broad-range protease inhibitor. Fetuin-A and cystatin C as endogenous proteolytic regulators of meprin activity broadens our understanding of the proteolytic network in plasma.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human Fetuin-A protein (TMPY-00801)
抗原种属
Human
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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