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Anti-NBN Antibody (9Z721)
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产品编号 TMAC-03044
别名 p95 protein of the MRE11/RAD50 complex, p95, Nijmegen breakage syndrome protein 1, Nijmegen breakage syndrome 1, Nijmegen breakage syndrome, Nibrin, nibrin, NBS1, NBS 1, NBS, MGC87362, FLJ10155, Cell cycle regulatory protein p95, ATV, AT V2, AT V1
Anti-NBN Antibody (9Z721) 是一种 Rabbit 抗体，靶向 NBN。Anti-NBN Antibody (9Z721) 可用于 WB,ICC/IF,IP,FCM,IHC,ChIP。
Anti-NBN Antibody (9Z721)
Anti-NBN Antibody (9Z721)
还可以产品编号 TMAC-03044 别名 p95 protein of the MRE11/RAD50 complex, p95, Nijmegen breakage syndrome protein 1, Nijmegen breakage syndrome 1, Nijmegen breakage syndrome, Nibrin, nibrin, NBS1, NBS 1, NBS, MGC87362, FLJ10155, Cell cycle regulatory protein p95, ATV, AT V2, AT V1
Anti-NBN Antibody (9Z721) 是一种 Rabbit 抗体，靶向 NBN。Anti-NBN Antibody (9Z721) 可用于 WB,ICC/IF,IP,FCM,IHC,ChIP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,480 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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| 产品描述 | Anti-NBN Antibody (9Z721) is a Rabbit antibody targeting NBN. Anti-NBN Antibody (9Z721) can be used in WB,ICC/IF,IP,FCM,IHC,ChIP. |
| 别名 | p95 protein of the MRE11/RAD50 complex, p95, Nijmegen breakage syndrome protein 1, Nijmegen breakage syndrome 1, Nijmegen breakage syndrome, Nibrin, nibrin, NBS1, NBS 1, NBS, MGC87362, FLJ10155, Cell cycle regulatory protein p95, ATV, AT V2, AT V1 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of Nibrin on human lung lysates using anti-p95 NBS1 antibody at 1/1,000 dilution. 2. ICC staining p95 NBS1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining p95 NBS1 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. Flow cytometric analysis of Hela cells with p95 NBS1antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:1000; IHC: 1:50; ICC/IF: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | DNA repair proteins are necessary for the maintenance of chromosome integrity and are involved in the elimination of premutagenic lesions from DNA. The DNA repair proteins Rad51 and Rad52 are key components of the double-strand-break repair (DSBR) pathway. Rad51 is essential for mitotic and meiotic recombination, and its mutation in yeast and mammalian cells results in chromosome loss. Overexpression of Rad52 confers resistance to ionizing radiation and induces homologous intrachromosomal recombination. Rad52 is thought to be involved in an early stage of Rad51-mediated recombination. Additional proteins involved in the pathway include Dmc1 and nibrin. Dmc1 is specifically involved in meiotic recombination. Nibrin, which complexes with Mre11 and Rad50, is absent in Nijemegen breakage syndrome (NBS) patients. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 95 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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