Anti-SEMA5A Polyclonal Antibody is a Rabbit antibody targeting SEMA5A. Anti-SEMA5A Polyclonal Antibody can be used in WB.

IgG

Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,Sheep,Zebrafish)

Sample:
A549 (Human) Cell Lysate at 30 μg
Primary: Anti-Semaphorin 5A (TMAB-01675) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 118 kDa
Observed band size: 118 kDa

WB: 1:500-2000

Polyclonal

KLH conjugated synthetic peptide: human Semaphorin 5A

Human

SEMA5A

Semaphorin-5A

Axonal Guidance Proteins,Neurogenesis,Neuroregeneration

Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs) (By similarity). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.