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Anti-DCPS Antibody (9T672)

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货号 TMAB-05010

Anti-DCPS Antibody (9T672) 是一种 Mouse 抗体，靶向 DCPS。Anti-DCPS Antibody (9T672) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-DCPS Antibody (9T672)

Anti-DCPS Antibody (9T672)

一键复制产品信息
Rating icon 还可以
货号 TMAB-05010

Anti-DCPS Antibody (9T672) 是一种 Mouse 抗体，靶向 DCPS。Anti-DCPS Antibody (9T672) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-DCPS Antibody (9T672) is a Mouse antibody targeting DCPS. Anti-DCPS Antibody (9T672) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG2b/Kappa
克隆号
9T672
反应种属
Human (predicted:Mouse)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cytoplasm. Nucleus.
组织特异性Detected in liver, brain, kidney, testis and prostate.
构建方式Recombinant Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Eukaryotic cells primarily utilize exoribonucleases and decapping enzymes to degrade their mRNA. DcpS is a scavenger pyrophosphatase that hydrolyzes the residual cap structure following 3' to 5' decay of an mRNA. Following mRNA degradation DcpS releases N-7 methyl guanosine monophosphate and 5'-diphosphate terminated cap or mRNA products. The central histidine within the DcpS HIT motif is critical for decapping activity and defines the HIT motif as a new mRNA decapping domain, making DcpS the first member of the HIT family of proteins with a defined biological function. HIT proteins are homodimeric and contain two conserved 100-amino-acid HIT fold domains with independent active sites that are each sufficient to bind and hydrolyze cognate substrates.
抗原信息
基因名称
DCPS
基因ID
28960
蛋白名称
m7GpppX diphosphatase
功能
Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'->5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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