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Anti-CRTC3 Antibody (9Y361)
还可以产品编号 TMAH-00301
别名 Transducer of regulated cAMP response element-binding protein 3, Transducer of CREB protein 3, TORC-3, TORC3, CREB-regulated transcription coactivator 3
Anti-CRTC3 Antibody (9Y361) 是一种抗体，靶向 CRTC3。Anti-CRTC3 Antibody (9Y361) 可用于 ELISA, IHC。
Anti-CRTC3 Antibody (9Y361)
Anti-CRTC3 Antibody (9Y361)
还可以产品编号 TMAH-00301 别名 Transducer of regulated cAMP response element-binding protein 3, Transducer of CREB protein 3, TORC-3, TORC3, CREB-regulated transcription coactivator 3
Anti-CRTC3 Antibody (9Y361) 是一种抗体，靶向 CRTC3。Anti-CRTC3 Antibody (9Y361) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,190 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CRTC3 Antibody (9Y361) is an antibody targeting CRTC3. Anti-CRTC3 Antibody (9Y361) can be used in ELISA, IHC. |
| 别名 | Transducer of regulated cAMP response element-binding protein 3, Transducer of CREB protein 3, TORC-3, TORC3, CREB-regulated transcription coactivator 3 |
| Ig Type | Rabbit IgG |
| 克隆号 | 9Y361 |
| 交叉反应 | Human |
| 验证活性 | IHC image of TMAH-00301 diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. |
| 应用 | ELISA, IHC |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Nucleus. Cytoplasm. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human CRTC3 |
| 抗原种属 | Human |
| 基因ID | 64784 |
| Uniprot ID | |
| 研究领域 | Epigenetics and Nuclear Signaling, Microbiology |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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