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Anti-Phospho-SREBP2 (Thr334) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-SREBP2 (Thr334)。Anti-Phospho-SREBP2 (Thr334) Polyclonal Antibody 可用于 WB。
Anti-Phospho-SREBP2 (Thr334) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-SREBP2 (Thr334)。Anti-Phospho-SREBP2 (Thr334) Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-Phospho-SREBP2 (Thr334) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SREBP2 (Thr334). Anti-Phospho-SREBP2 (Thr334) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat (predicted:Chicken,Pig,Cow,Horse,Rabbit,Sheep) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Note=Moves from the endoplasmic reticulum to the Golgi in the absence of sterols. Processed sterol regulatory element-binding protein 2: Nucleus. |
| 组织特异性 | Ubiquitously expressed in adult and fetal tissues. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human SREBP2 around the phosphorylation site of Thr334 |
| 抗原种属 | Human |
| 基因名称 | SREBF2 |
| 基因ID | |
| 蛋白名称 | Sterol regulatory element-binding protein 2 |
| Uniprot ID | |
| 功能 | Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity). Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes. |
| 分子量 | Theoretical: 126 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |