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Anti-KDM4B Antibody (3X256) 是一种 Rabbit 抗体,靶向 KDM4B。Anti-KDM4B Antibody (3X256) 可用于 WB,ICC/IF,FCM,IHC-P,IHC-Fr,IF。
Anti-KDM4B Antibody (3X256) 是一种 Rabbit 抗体,靶向 KDM4B。Anti-KDM4B Antibody (3X256) 可用于 WB,ICC/IF,FCM,IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 780 | 5日内发货 | |
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-KDM4B Antibody (3X256) is a Rabbit antibody targeting KDM4B. Anti-KDM4B Antibody (3X256) can be used in WB,ICC/IF,FCM,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 克隆号 | 3X256 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBICC/IFFCMIHC-PIHC-FrIF |
| 推荐剂量 | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. Chromosome. Associates with euchromatic regions. Does not associate with heterochromatin. |
| 组织特异性 | Expressed in all tissues examined, with high levels in fetal liver, thymus, lymph node, spleen and peripheral blood leukocytes and lower level in bone marrow. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Enables histone H3-methyl-lysine-36 demethylase activity and histone H3-methyl-lysine-9 demethylase activity. Involved in histone H3-K36 demethylation and histone H3-K9 demethylation. Located in cytosol and nucleoplasm. Implicated in autosomal dominant non-syndromic intellectual disability; breast cancer; colorectal cancer; malignant peripheral nerve sheath tumor; and stomach cancer. Biomarker of several diseases, including alopecia areata; lung cancer; medulloblastoma; prostate cancer; and stomach cancer. [provided by Alliance of Genome Resources, Apr 2022] |
| 基因名称 | KDM4B |
| 基因ID | |
| 蛋白名称 | Lysine-specific demethylase 4B |
| 功能 | Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. |
| 分子量 | Theoretical: 122 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |