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Anti-SOD1 Antibody (9S890)

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Anti-SOD1 Antibody (9S890)
产品编号 TMAY-02023
别名 superoxide dismutase 1, soluble, SOD, IPOA, hSod1, homodimer, HEL-S-44, ALS1, ALS

Anti-SOD1 Antibody (9S890) 是一种 Rabbit 抗体,靶向 SOD1。Anti-SOD1 Antibody (9S890) 可用于 ELISA,ICC/IF。

Anti-SOD1 Antibody (9S890)
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Anti-SOD1 Antibody (9S890)

Rating icon 还可以
Anti-SOD1 Antibody (9S890)
产品编号 TMAY-02023 别名 superoxide dismutase 1, soluble, SOD, IPOA, hSod1, homodimer, HEL-S-44, ALS1, ALS

Anti-SOD1 Antibody (9S890) 是一种 Rabbit 抗体,靶向 SOD1。Anti-SOD1 Antibody (9S890) 可用于 ELISA,ICC/IF。

规格价格库存数量
100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-SOD1 Antibody (9S890) is a Rabbit antibody targeting SOD1. Anti-SOD1 Antibody (9S890) can be used in ELISA,ICC/IF.
别名superoxide dismutase 1, soluble, SOD, IPOA, hSod1, homodimer, HEL-S-44, ALS1, ALS
Ig Type
Rabbit IgG
克隆号
9S890
交叉反应
Human
验证活性
Immunofluorescence staining of Human SOD1 in Hela cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with rabbit anti-Human SOD1 monoclonal antibody (1:60). Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm.
应用
ELISA,ICC/IF
推荐剂量
ELISA: 1:5000-1:10000; ICC-IF: 1:20-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human SOD1 (rh SOD1; TMPY-01585; NP_000445.1; Ala 2-Gln 154).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景SOD1 belongs to the Cu-Zn superoxide dismutase family. It binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. SOD1 destroys radicals which are normally produced within the cells and which are toxic to biological systems. Defects in SOD1 are the cause of amyotrophic lateral sclerosis type 1 (ALS1). ALS1 is a familial form of amyotrophic lateral sclerosis, a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors. The disease is inherited in 5-10% of cases leading to familial forms.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human SOD1 protein (TMPY-01585)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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