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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Agrin Polyclonal Antibody

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货号 TMAB-02387

Anti-Agrin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Agrin。Anti-Agrin Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Agrin Polyclonal Antibody

Anti-Agrin Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-02387

Anti-Agrin Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Agrin。Anti-Agrin Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
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100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Agrin Polyclonal Antibody is a Rabbit antibody targeting Agrin. Anti-Agrin Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Cow,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted, extracellular space, extracellular matrix. Note=Synaptic basal lamina at the neuromuscular junction.
组织特异性Detected on the aortic endothelium (at protein level).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. [provided by RefSeq, Aug 2011].
抗原信息
免疫原
KLH conjugated synthetic peptide: human Agrin
抗原种属
Human
基因名称
AGRN
基因ID
375790
蛋白名称
Agrin
Uniprot ID
O00468
功能
Plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Ligand of the MUSK signaling complex that directly binds LRP4 in this complex and induces the phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane.
化学信息
分子量Theoretical: 213 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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