Anti-GCG Antibody (5D789)

Name: Anti-GCG Antibody (5D789)
Brand: TargetMol
SKU: TMAH-00478
Rating: 4.5 (1 reviews)

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产品编号 TMAH-00478

别名 Oxyntomodulin, OXY, OXM, Incretin Hormone, GRPP, Glucagon-Like Peptide 2, Glucagon-Like Peptide 1, Glucagon, GLP-2, GLP-1, Glicentin-Related Polypeptide, Glicentin, GCG

Anti-GCG Antibody (5D789) 是一种抗体，靶向 GCG。Anti-GCG Antibody (5D789) 可用于 ELISA。

Anti-GCG Antibody (5D789)

还可以

产品编号 TMAH-00478 别名 Oxyntomodulin, OXY, OXM, Incretin Hormone, GRPP, Glucagon-Like Peptide 2, Glucagon-Like Peptide 1, Glucagon, GLP-2, GLP-1, Glicentin-Related Polypeptide, Glicentin, GCG

Anti-GCG Antibody (5D789) 是一种抗体，靶向 GCG。Anti-GCG Antibody (5D789) 可用于 ELISA。

规格	价格	库存	数量
50 μL	¥ 1,300	5日内发货
100 μL	¥ 2,180	5日内发货

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产品描述	Anti-GCG Antibody (5D789) is an antibody targeting GCG. Anti-GCG Antibody (5D789) can be used in ELISA.
别名	Oxyntomodulin, OXY, OXM, Incretin Hormone, GRPP, Glucagon-Like Peptide 2, Glucagon-Like Peptide 1, Glucagon, GLP-2, GLP-1, Glicentin-Related Polypeptide, Glicentin, GCG
Ig Type	Rabbit IgG
克隆号	5D789
交叉反应	Human
应用	ELISA
抗体种类	Monoclonal
亚细胞定位	Secreted.; [Glucagon-like peptide 1]: Secreted.
构建方式	Recombinant Antibody
纯化方式	Affinity-chromatography
性状	Liquid
缓冲液	Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景	Plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. Potent stimulator of glucose-dependent insulin release. Also stimulates insulin release in response to IL6. Plays important roles on gastric motility and the suppression of plasma glucagon levels. May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin. Has growth-promoting activities on intestinal epithelium. May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin secretion. Increases islet mass through stimulation of islet neogenesis and pancreatic beta cell proliferation. Inhibits beta cell apoptosis. Stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a key role in nutrient homeostasis, enhancing nutrient assimilation through enhanced gastrointestinal function, as well as increasing nutrient disposal. Stimulates intestinal glucose transport and decreases mucosal permeability. Significantly reduces food intake. Inhibits gastric emptying in humans. Suppression of gastric emptying may lead to increased gastric distension, which may contribute to satiety by causing a sensation of fullness. May modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life.