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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GGH Polyclonal Antibody

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货号 TMAB-06455

Anti-GGH Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GGH。Anti-GGH Polyclonal Antibody 可用于 WB。

Anti-GGH Polyclonal Antibody

Anti-GGH Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06455

Anti-GGH Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GGH。Anti-GGH Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-GGH Polyclonal Antibody is a Rabbit antibody targeting GGH. Anti-GGH Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted; extracellular space. Lysosome. Melanosome. While its intracellular location is primarily the lysosome, most of the enzyme activity is secreted. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
浓度1mg/ml
研究背景GGH is a 318 amino acid protein that is secreted into the extracellular space and is also localized to both the lysosome and the melanosome. Functioning as a hydrolase, GGH contains one gamma-glutamyl hydrolase domain through which it catalyzes the hydrolysis of polyglutamate sidechains from pteroylpolyglutamates, specifically hydrolyzing gamma-glutamyl bonds. Via its catalytic activity, GGH may play a role in the bioavailability and metabolic activity of pteroylpolyglutamates. Polymorphisms in the gene encoding GGH are associated with rheumatoid arthritis, inflammatory bowel disease and various cancers. The gene encoding GGH maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GGH
抗原种属
Human
基因名称
GGH
基因ID
8836
蛋白名称
gamma-glutamyl hydrolase
Uniprot ID
Q92820
功能
Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.
化学信息
分子量Theoretical: 34 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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