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Anti-Renin Antibody (1I520) 是一种 Mouse 抗体,靶向 Renin。Anti-Renin Antibody (1I520) 可用于 IHC-P,WB,IHC-Fr,IF。
Anti-Renin Antibody (1I520) 是一种 Mouse 抗体,靶向 Renin。Anti-Renin Antibody (1I520) 可用于 IHC-P,WB,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 200 μg | ¥ 5,590 | 5日内发货 | |
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-Renin Antibody (1I520) is a Mouse antibody targeting Renin. Anti-Renin Antibody (1I520) can be used in IHC-P,WB,IHC-Fr,IF. |
| 克隆号 | 1I520 |
| 反应种属 | Human |
| 应用 | IHC-PWBIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; WB: 1:500-2000; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Secreted. Membrane. Associated to membranes via binding to ATP6AP2. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | PBS (pH7.4). |
| 研究背景 | Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]. |
| 免疫原 | Recombinant Protein: human Renin protein |
| 抗原种属 | Human |
| 基因名称 | REN |
| 基因ID | |
| 蛋白名称 | Renin |
| Uniprot ID | |
| 功能 | Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. |
| 分子量 | Theoretical: 37 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |