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顶部生物活性储存和溶解信息计算器

Anti-ENTPD5 Antibody (8M811)

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Anti-ENTPD5 Antibody (8M811)
产品编号 TMAY-01723
别名 Pcph, NTPDase-5, NTPDase5, mNTPase, ER-UDPase, ectonucleoside triphosphate diphosphohydrolase 5, Cd39l4, AI987697, AI196558

Anti-ENTPD5 Antibody (8M811) 是一种 Mouse 抗体，靶向 ENTPD5。Anti-ENTPD5 Antibody (8M811) 可用于 IHC-P。

Anti-ENTPD5 Antibody (8M811)
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Anti-ENTPD5 Antibody (8M811)

Rating icon 还可以
Anti-ENTPD5 Antibody (8M811)
产品编号 TMAY-01723 别名 Pcph, NTPDase-5, NTPDase5, mNTPase, ER-UDPase, ectonucleoside triphosphate diphosphohydrolase 5, Cd39l4, AI987697, AI196558

Anti-ENTPD5 Antibody (8M811) 是一种 Mouse 抗体，靶向 ENTPD5。Anti-ENTPD5 Antibody (8M811) 可用于 IHC-P。

规格价格库存数量
100 μL
¥ 1,679
5日内发货
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产品介绍

生物活性
产品描述
Anti-ENTPD5 Antibody (8M811) is a Mouse antibody targeting ENTPD5. Anti-ENTPD5 Antibody (8M811) can be used in IHC-P.
别名Pcph, NTPDase-5, NTPDase5, mNTPase, ER-UDPase, ectonucleoside triphosphate diphosphohydrolase 5, Cd39l4, AI987697, AI196558
Ig Type
Mouse IgG1
克隆号
8M811
交叉反应
Human
验证活性
1. Immunochemical staining of human ENTPD5 in human prostate with mouse monoclonal antibody (1:30, formalin-fixed paraffin embedded sections).
2. Immunochemical staining of human ENTPD5 in human kidney with mouse monoclonal antibody (1:30, formalin-fixed paraffin embedded sections).
应用
IHC-P
推荐剂量
IHC-P: 1:20-1:100
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ENTPD5 (rh ENTPD5; TMPY-02758; O75356; Met1-His428). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5), also known as CD39 antigen-like 4, ER-UDPase, Guanosine-diphosphatase ENTPD5, Nucleoside diphosphatase Uridine-diphosphatase ENTPD5. This hydrolase is expressed in response to phosphoinositide 3-kinase (PI3K) signaling. Activation of PI3K results in FOXO phosphorylation by AKT1 and loss of ENTPD5 transcriptional repression. It is Up-regulated in PTEN-deficient cells. Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation.ENTPD5 promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, ENTPD5 constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. ENTPD5 also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. This enzyme Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human ENTPD5 Protein (TMPY-02758)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

AI-987697AI-196558AI 987697AI 196558

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