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Anti-ISL1 Antibody (8S951)

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Anti-ISL1 Antibody (8S951)
产品编号 TMAC-02245
别名 Islet-1, ISL 1, Insulin gene enhancer protein ISL-1

Anti-ISL1 Antibody (8S951) 是一种 Rabbit 抗体,靶向 ISL1。Anti-ISL1 Antibody (8S951) 可用于 WB,ICC/IF,IP。

Anti-ISL1 Antibody (8S951)

Anti-ISL1 Antibody (8S951)

Rating icon 还可以
Anti-ISL1 Antibody (8S951)
产品编号 TMAC-02245 别名 Islet-1, ISL 1, Insulin gene enhancer protein ISL-1

Anti-ISL1 Antibody (8S951) 是一种 Rabbit 抗体,靶向 ISL1。Anti-ISL1 Antibody (8S951) 可用于 WB,ICC/IF,IP。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-ISL1 Antibody (8S951) is a Rabbit antibody targeting ISL1. Anti-ISL1 Antibody (8S951) can be used in WB,ICC/IF,IP.
别名Islet-1, ISL 1, Insulin gene enhancer protein ISL-1
Ig Type
IgG
交叉反应
Human,Mouse
验证活性
1. Western blot analysis of Islet 1 on MCF-7 cell lysates using anti-Islet 1 antibody at 1/1,000 dilution.
2. ICC staining Islet 1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
推荐剂量
WB: 1:1000; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Islet-1 (ISL1 transcription factor, LIM/homeodomain) and Islet-2 (ISL2 transcription factor, LIM/homeodomain) contain amino-terminal LIM domains and a carboxy-terminal homeodomain and both influence developmental events. Islet-1 influences embryogenesis of the pancreatic islets of Langerhans and neural tube motor neuron differentiation. In developing mouse teeth, Islet-1 mediates patterning of dentition as an activator of Bmp4 expression in incisor (distal) areas of the stomatodeal epithelium. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Islet-2 activity in newly generated motor neurons permits the diversification of visceral and somatic motor neuron subtypes in the developing spinal cord. Murine Islet-2 specifies retinal ganglion cell (RGC) laterality by repressing an ipsilateral pathfinding program unique to the ventral-temporal crescent (VTC) of RGCs in a Zic2- and EphB1-dependent manner.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 39 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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