Name: TNFSF12/TWEAK Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPK-00727
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 343

6-8日内发货

10 μg

¥ 549

6-8日内发货

20 μg

¥ 898

5日内发货

50 μg

¥ 1,760

5日内发货

100 μg

¥ 2,960

5日内发货

200 μg

¥ 5,350

5日内发货

500 μg

¥ 11,800

5日内发货

生物活性

产品描述	Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a well known multifunctional cytokine extensively distributed in cell types and tissues. Accumulating evidence has shown that TWEAK binding to the receptor factor-inducible 14 (Fn14) participates in diverse pathologic processes including cell proliferation and death, angiogenesis, carcinogenesis and inflammation.
生物活性	1. Immobilized Human TNFSF12, hFc Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-TNFSF12 Antibody, hFc Tag with the EC50 of 0.11μg/ml determined by ELISA (QC Test). 2. Human TNFSF12, hFc Tag immobilized on CM5 Chip can bind Human TNFRSF12A, hFc Tag with an affinity constant of 0.24 nM as determined in SPR assay.
研究背景	Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a well known multifunctional cytokine extensively distributed in cell types and tissues. Accumulating evidence has shown that TWEAK binding to the receptor factor-inducible 14 (Fn14) participates in diverse pathologic processes including cell proliferation and death, angiogenesis, carcinogenesis and inflammation.
种属	Human
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	O43508-1
蛋白构建	Ser43-His249
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 200 mM L-arginine (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	UNQ181/PRO207, TWEAK, MGC129581, DR3LG, APO3L, APO3 ligand
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	49.62 kDa (predicted). Due to enzyme lysis and glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

TNFSF12/TWEAK Protein, Human, Recombinant (hFc)

TNFSF12/TWEAK Protein, Human, Recombinant (hFc)

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