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Anti-CD46 Antibody (2T922)
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产品编号 TMAY-02295
别名 TRA2.10, TLX, MIC10, MCP, CD46 molecule, complement regulatory protein, AHUS2
Anti-CD46 Antibody (2T922) 是一种 Rabbit 抗体，靶向 CD46。Anti-CD46 Antibody (2T922) 可用于 ELISA,IHC-P,ICC/IF。
Anti-CD46 Antibody (2T922)
Anti-CD46 Antibody (2T922)
还可以产品编号 TMAY-02295 别名 TRA2.10, TLX, MIC10, MCP, CD46 molecule, complement regulatory protein, AHUS2
Anti-CD46 Antibody (2T922) 是一种 Rabbit 抗体，靶向 CD46。Anti-CD46 Antibody (2T922) 可用于 ELISA,IHC-P,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,279 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CD46 Antibody (2T922) is a Rabbit antibody targeting CD46. Anti-CD46 Antibody (2T922) can be used in ELISA,IHC-P,ICC/IF. |
| 别名 | TRA2.10, TLX, MIC10, MCP, CD46 molecule, complement regulatory protein, AHUS2 |
| Ig Type | Rabbit IgG |
| 克隆号 | 2T922 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human CD46 in human placenta with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to membrane of trophoblast. 2. Immunofluorescence staining of CD46 in HepG2 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-human CD46 monoclonal antibody (1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). |
| 应用 | |
| 推荐剂量 | ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500; ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD46 (rh CD46; TMPY-02023; EAW93471.1; Met1-Asp328). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white blood cells, platelets, epithelial cells, and fibroblasts. Human CD46 shares 5% amino acid sequence identity with mouse and rat CD46. The importance of CD46 to complement regulation is underscored by the observation that genetic loss of CD46 leads to development of atypical hemolytic-uremic syndrome (aHUS), a disease characterized by uncontrolled complement activation. CD46 is implicated in the development and/or progression of selected cancer types. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human CD46 protein (TMPY-02023) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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