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Anti-C1 inhibitor Antibody-HRP (7X93)

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产品编号 TMAY-01438H

Anti-C1 inhibitor Antibody-HRP (7X93) 是一种 HRP-conjugated Rabbit 抗体,靶向 C1 inhibitor。Anti-C1 inhibitor Antibody-HRP (7X93) 可用于 ELISA。

Anti-C1 inhibitor Antibody-HRP (7X93)

Anti-C1 inhibitor Antibody-HRP (7X93)

Rating icon 还可以
产品编号 TMAY-01438H

Anti-C1 inhibitor Antibody-HRP (7X93) 是一种 HRP-conjugated Rabbit 抗体,靶向 C1 inhibitor。Anti-C1 inhibitor Antibody-HRP (7X93) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-C1 inhibitor Antibody-HRP (7X93) is a HRP-conjugated Rabbit antibody targeting C1 inhibitor. Anti-C1 inhibitor Antibody-HRP (7X93) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
7X93
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 0.1-1 μg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human SerpinG1 (rh SerpinG1; TMPY-01183; NP_000053.2; Met 1-Ala 500), and conjugated with horseradish-peroxidase (HRP).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact systems. By its C-terminal part (serpin domain), characterized by three beta-sheets and an exposed mobile reactive loop, C1-INH binds, and blocks the activity of its target proteases. The N-terminal end (nonserpin domain) confers to C1-INH the capacity to bind lipopolysaccharides and E-selectin. Owing to this moiety, C1-INH intervenes in regulation of the inflammatory reaction. The heterozygous deficiency of C1-INH results in hereditary angioedema (HAE). Owing to its ability to modulate the contact and complement systems and the convincing safety profile, plasma-derived C1 inhibitor is an attractive therapeutic protein to treat inflammatory diseases other than HAE. Deficiency of C1 inhibitor results in hereditary angioedema, which is characterized by recurrent episodes of localized angioedema of the skin, gastrointestinal mucosa or upper respiratory mucosa. C1 inhibitor may prove useful in a variety of other diseases including septic shock, reperfusion injury, hyperacute transplant rejection, traumatic and hemorrhagic shock, and the increased vascular permeability associated with thermal injury, interleukin-2 therapy and cardiopulmonary bypass.
偶联与修饰
偶联
HRP
其他可选修饰符
Unconjugated
可提供抗体种类
2
抗原信息
免疫原
Recombinant Human SerpinG1 protein (TMPY-01183)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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