Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Xanthine amine congener dihydrochloride (XAC dihydrochloride), a potent antagonist for both Adenosine A1 and A2 receptors, exhibits IC50 values of 1.8 nM for A1 and 114 nM for A2 receptors. Additionally, it functions as a convulsant agent in mouse models.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 mg | ¥ 3,270 | 35日内发货 | ||
50 mg | ¥ 13,500 | 35日内发货 |
Xanthine amine congener dihydrochloride 的其他形式现货产品:
产品描述 | Xanthine amine congener dihydrochloride (XAC dihydrochloride), a potent antagonist for both Adenosine A1 and A2 receptors, exhibits IC50 values of 1.8 nM for A1 and 114 nM for A2 receptors. Additionally, it functions as a convulsant agent in mouse models. |
靶点活性 | A1 receptor:1.8 nM (IC50), A2 receptor:114 nM (IC50) |
体内活性 | Xanthine amine congener dihydrochloride is more potent as a convulsant than either caffeine or theophyllin in infusion studies at the dosage 39.8 mg/kg. XAC has no effects by administering the drug via an i.p. injection, the seizure threshold >1000 mg/kg[1]. Animal Model: Mice[1]Dosage: 39.8 mg/kg Administration: Infusion injection; single dose Result: Acted as a convulsant agent than either caffeine or theophyllin. |
别名 | XAC dihydrochloride, Xanthine amine congener dihydrochloride |
分子量 | 501.41 |
分子式 | C21H30Cl2N6O4 |
CAS No. | 1962928-23-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Xanthine amine congener dihydrochloride 1962928-23-9 Xanthine amine congener XAC dihydrochloride XAC Dihydrochloride Xanthine amine congener Dihydrochloride XAC Inhibitor inhibitor inhibit