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Anti-GM-CSFR alpha Antibody-FITC (5S90) 是一种 FITC-conjugated Rabbit 抗体,靶向 GM-CSFR alpha。Anti-GM-CSFR alpha Antibody-FITC (5S90) 可用于 FCM。
Anti-GM-CSFR alpha Antibody-FITC (5S90) 是一种 FITC-conjugated Rabbit 抗体,靶向 GM-CSFR alpha。Anti-GM-CSFR alpha Antibody-FITC (5S90) 可用于 FCM。
产品描述 | Anti-GM-CSFR alpha Antibody-FITC (5S90) is a FITC-conjugated Rabbit antibody targeting GM-CSFR alpha. Anti-GM-CSFR alpha Antibody-FITC (5S90) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 5S90 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of anti-human GM-CSFRa(CD116) on human peripheral blood monocytes. The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable monocytes. |
应用 | FCM |
推荐剂量 | 10 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD116 / GM-CSFR (rh CD116 / GM-CSFR; TMPY-01065; P15509-1; Met1-Gly320) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
研究背景 | CD116/GM-CSFR has been preferentially associated with M4, M5 subtype of AML but is not specific. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Physiologically, CD molecules can act in numerous ways, often acting as receptors or ligands (the molecule that activates a receptor) important to the cell. A signal cascade is usually initiated, altering the behavior of the cell (see cell signaling). Some CD proteins do not play a role in cell signaling, but have other functions, such as cell adhesion. CD116/GM-CSFR is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. CD116/GM-CSFR is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. |
偶联 | FITC |
其他可选修饰符 | Unconjugated/APC/PE |
可提供抗体种类 | 4 |
免疫原 | Recombinant Human CD116 / GM-CSFR protein (TMPY-01065) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
运输方式 | Shipping with blue ice. |
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